Methyl Indoline-6-carboxylate
- Product Name
- Methyl Indoline-6-carboxylate
- CAS No.
- 341988-36-1
- Chemical Name
- Methyl Indoline-6-carboxylate
- Synonyms
- methyl indoline-6-carboxylate;methyl indoline-6-carboxylate - [M23157];Methyl 2,3-dihydro-1H-indole-6-carboxylate;Methyl2,3-dihydro-1H-indole-6-carboxylatato;Methyl indoline-6-carboxylate in stock Factory;1H-INDOLE-6-CARBOXYLIC ACID,2,3-DIHYDRO-,METHYL ESTER;2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE
- CBNumber
- CB7843433
- Molecular Formula
- C10H11NO2
- Formula Weight
- 177.2
- MOL File
- 341988-36-1.mol
Methyl Indoline-6-carboxylate Property
- Boiling point:
- 315.6±31.0 °C(Predicted)
- Density
- 1.162±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 4.26±0.20(Predicted)
- Appearance
- White to yellow Solid
- InChI
- InChI=1S/C10H11NO2/c1-13-10(12)8-3-2-7-4-5-11-9(7)6-8/h2-3,6,11H,4-5H2,1H3
- InChIKey
- IVFIWGSRKYSLLR-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=CC(C(OC)=O)=C2)CC1
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- M313608
- Product name
- Methylindoline-6-carboxylate
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FD56698
- Product name
- 2,3-Dihydro-1H-indole-6-carboxylic acid methyl ester
- Packaging
- 25mg
- Price
- $88.5
- Updated
- 2021/12/16
- Product number
- W5567
- Product name
- Methylindoline-6-carboxylate
- Packaging
- 250mg
- Price
- $151
- Updated
- 2021/12/16
- Product number
- FD56698
- Product name
- 2,3-Dihydro-1H-indole-6-carboxylic acid methyl ester
- Packaging
- 50mg
- Price
- $181
- Updated
- 2021/12/16
- Product number
- OR910526
- Product name
- Methylindoline-6-carboxylate
- Purity
- 98%
- Packaging
- 1g
- Price
- $230
- Updated
- 2021/12/16
Methyl Indoline-6-carboxylate Chemical Properties,Usage,Production
Chemical Properties
White solid
Synthesis
50820-65-0
341988-36-1
Step 1: Methyl indole-6-carboxylate (534 mg, 3.05 mmol) was dissolved in acetic acid (7.5 mL) and the solution was cooled to 0°C. Sodium cyanoborohydride (580 mg, 9.2 mmol, 3 equiv) was added to the solution in batches with stirring. The reaction mixture was stirred continuously for 40 minutes at 15 °C. Subsequently, sodium cyanoborohydride (193 mg, 3.05 mmol, 1 eq.) was added again and stirring was continued for 30 minutes at room temperature. After completion of the reaction, the solvent was removed by rotary evaporator. The residue was dissolved in dichloromethane and washed with 1N NaOH solution. The organic phase was dried over anhydrous sodium sulfate, filtered and concentrated to afford methyl 2,3-dihydro-1H-indole-6-carboxylate as a pale yellow solid in a yield of 494 mg (77% yield). The product did not require further purification and could be used directly in the subsequent reaction.
References
[1] Patent: US2007/60567, 2007, A1. Location in patent: Page/Page column 25
[2] Patent: US2008/153805, 2008, A1. Location in patent: Page/Page column 12
[3] ChemMedChem, 2016, vol. 11, # 23, p. 2607 - 2620
[4] Patent: WO2018/52903, 2018, A1. Location in patent: Page/Page column 22; 43-44
[5] Patent: US2010/234340, 2010, A1. Location in patent: Page/Page column 20
Methyl Indoline-6-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl Indoline-6-carboxylate manufacturers
- Product
- Methyl 2,3-dihydro-1H-indole-6-carboxylate 341988-36-1
- Price
- US $1.10-9.90/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 100kg
- Release date
- 2025-08-18
- Product
- Methyl indoline-6-carboxylate in stock Factory 341988-36-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- TOP 3 Factory in China
- Supply Ability
- Top 3 production capacity Factory
- Release date
- 2019-04-03
- Product
- 2,3-DIHYDRO-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE 341988-36-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 200kgs
- Release date
- 2020-01-09