ChemicalBook > CAS DataBase List > LP 44
LP 44
- Product Name
- LP 44
- CAS No.
- 824958-12-5
- Chemical Name
- LP 44
- Synonyms
- LP 44;LP44 (hydrochloride);LP-44, 5-HT7 agonist;compound 5 [PMID 17649988].;4-[2-(Methylthio)phenyl]-N-(1,2,3,4-tetrahydro-1-naphthalenyl)-1-piperazinehexanamidehydrochlo;4-[2-(Methylthio)phenyl]-N-(1,2,3,4-tetrahydro-1-naphth alenyl)-1-piperazinehexanamide hydrochloride;6-[4-(2-methylsulfanylphenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide:hydrochloride
- CBNumber
- CB7846621
- Molecular Formula
- C27H37N3OS.ClH
- Formula Weight
- 488.136
- MOL File
- 824958-12-5.mol
More
Less
LP 44 Property
- storage temp.
- 2-8°C
- solubility
- DMSO: >10mg/mL
- form
- solid
- color
- White to off-white
More
Less
Safety
- WGK Germany
- 3
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- L9793
- Product name
- LP44
- Purity
- ≥98% (HPLC), solid
- Packaging
- 10mg
- Price
- $203
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- L9793
- Product name
- LP44
- Purity
- ≥98% (HPLC), solid
- Packaging
- 50mg
- Price
- $806
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 5.08155
- Product name
- LP-44 Hydrochloride - CAS 824958-12-5 - Calbiochem
- Packaging
- 10MG
- Price
- $205
- Updated
- 2022/05/15
Cayman Chemical
- Product number
- 17287
- Product name
- LP44 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17287
- Product name
- LP44 (hydrochloride)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $109
- Updated
- 2024/03/01
More
Less
LP 44 Chemical Properties,Usage,Production
Uses
LP 44 Hydrochloride is used in the preparation of (tetrahydronaphthalenyl)arylpiperazinealkylamides which an agonist of the serotonin 5-HT7 receptor.
Biological Activity
High affinity 5-HT 7 receptor agonist (K i = 0.22 nM) that displays selectivity over 5-HT 1A and 5-HT 2A receptors (200- and > 1000-fold respectively). Induces relaxation of substance P-stimulated guinea pig ileum (EC 50 = 2.56 μ M).
in vivo
LP44 (hydrochloride) (5.1, 10.3, 20.5, 41.0 nmol; i.c.v.) produces dose-dependent hypothermic effect in CBA mice[1].
LP 44 Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
LP 44 Suppliers
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- 888-539-0666
- Fax
- 888-539-0666
- info@emmx.com
- Country
- United States
- ProdList
- 8447
- Advantage
- 60
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- 18818260767
- Fax
- QQ 3610331285
- sales@chemegen.com
- Country
- China
- ProdList
- 11218
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing@energy-chemical.com
- Country
- China
- ProdList
- 44918
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24961
- Advantage
- 58
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
- Country
- China
- ProdList
- 11973
- Advantage
- 58
- Tel
- 18024082417
- market@ubiochem.com
- Country
- China
- ProdList
- 9835
- Advantage
- 58
- Tel
- 40-15317324578 4008100881
- atcc@sinozhongyuan.com
- Country
- China
- ProdList
- 3344
- Advantage
- 58
- Tel
- 800-364-9897
- sales@caymanchem.com
- Country
- China
- ProdList
- 6838
- Advantage
- 58