2-BROMOTHIOPHENE-3-CARBALDEHYDE
- Product Name
- 2-BROMOTHIOPHENE-3-CARBALDEHYDE
- CAS No.
- 1860-99-7
- Chemical Name
- 2-BROMOTHIOPHENE-3-CARBALDEHYDE
- Synonyms
- JACS-1860-99-7;2-Bromo-3-formylthiophene;2-Bromo-3-thiophenecarbaldehyde;2-BROMOTHIOPHENE-3-CARBALDEHYDE;2-Bromothiophene-3-carboxaldehyde;2-Bromo-3-thiophenecarboxaldehyde;3-Thiophenecarboxaldehyde, 2-bromo-;2-Bromothiophene-3-carboxaldehyde97%;2-Bromothiophene-3-carboxaldehyde 97%;2-Bromothiophene-3-carbaldehyde(stabilized with Cu+HQ+MgO)
- CBNumber
- CB7847628
- Molecular Formula
- C5H3BrOS
- Formula Weight
- 191.05
- MOL File
- 1860-99-7.mol
2-BROMOTHIOPHENE-3-CARBALDEHYDE Property
- Boiling point:
- 60 °C
- Density
- 1.789±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- fused solid
- color
- Very dark red/brown
- InChI
- InChI=1S/C5H3BrOS/c6-5-4(3-7)1-2-8-5/h1-3H
- InChIKey
- MMEGVQIGIBCTHI-UHFFFAOYSA-N
- SMILES
- C1(Br)SC=CC=1C=O
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CDS015492
- Product name
- 2-bromothiophene-3-carbaldehyde
- Purity
- AldrichCPR
- Packaging
- 100MG
- Price
- $107
- Updated
- 2025/07/31
- Product number
- B428573
- Product name
- 2-bromothiophene-3-carbaldehyde
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- P000491981
- Product name
- 2-Bromothiophene-3-carbaldehyde
- Purity
- 97%
- Packaging
- 100mg
- Price
- $26
- Updated
- 2021/12/16
- Product number
- P000491981
- Product name
- 2-Bromothiophene-3-carbaldehyde
- Purity
- 97%
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- P000491981
- Product name
- 2-Bromothiophene-3-carbaldehyde
- Purity
- 97%
- Packaging
- 1g
- Price
- $90
- Updated
- 2021/12/16
2-BROMOTHIOPHENE-3-CARBALDEHYDE Chemical Properties,Usage,Production
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 13, p. 1099, 1976 DOI: 10.1002/jhet.5570130534
Synthesis
40032-76-6
1860-99-7
The general procedure for the synthesis of 2-bromothiophene-3-carboxaldehyde from 2-bromo-3-bromomethylthiophene is as follows: in a 250-mL two-necked flask, 11.9 g (46 mmol) of undried 2-bromo-3-(bromomethyl)thiophene (molecular weight 256 g/mol) was added. Under nitrogen protection, 20.8 g (74 mmol, 1.6 eq.) of IBX (molecular weight 280 g/mol) and 130 mL of anhydrous DMSO were added to the reaction system.The reaction mixture was heated in an oil bath at 60-70 °C for 3-4 h. The reaction was completed by the addition of 20.8 g (74 mmol, 1.6 eq.) of IBX (molecular weight 280 g/mol) and 130 mL of anhydrous DMSO. Upon completion of the reaction, 20 mL of deionized water was added to quench the reaction. The reaction mixture was extracted with dichloromethane and the precipitate was washed with plenty of dichloromethane to give a white solid. The filtrate was collected by filtration, subsequently dried and purified by column chromatography with the eluent being petroleum ether/ethyl acetate (40:1, V/V).
References
[1] Journal of the American Chemical Society, 2014, vol. 136, # 19, p. 7132 - 7139
[2] Patent: CN106588868, 2017, A. Location in patent: Paragraph 0025; 0034; 0035; 0036; 0037
[3] Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1983, p. 813 - 820
2-BROMOTHIOPHENE-3-CARBALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-BROMOTHIOPHENE-3-CARBALDEHYDE manufacturers
- Product
- 2-BROMOTHIOPHENE-3-CARBALDEHYDE 1860-99-7
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-08