1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE
- Product Name
- 1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE
- CAS No.
- 340771-31-5
- Chemical Name
- 1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE
- Synonyms
- 1-Ethynyl-4-(methylsulfonyl);4-(Methylsulfonyl)phenylacetylene;1-Ethynyl-4-(Methylsulfonyl)benzene;1-Ethynyl-4-Methanesulfonyl-benzene;1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE;Benzene, 1-ethynyl-4-(Methylsulfonyl)-;1-Ethynyl-4-(methylsulfonyl)benzene - [E51620]
- CBNumber
- CB7848564
- Molecular Formula
- C9H8O2S
- Formula Weight
- 180.22
- MOL File
- 340771-31-5.mol
1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE Property
- Boiling point:
- 327.7±34.0 °C(Predicted)
- Density
- 1.25±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P363Wash contaminated clothing before reuse.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- E945785
- Product name
- 1-Ethynyl-4-(methylsulfonyl)benzene
- Packaging
- 500mg
- Price
- $285
- Updated
- 2021/12/16
- Product number
- E51620
- Product name
- 1-Ethynyl-4-(methylsulfonyl)benzene
- Purity
- 95%
- Packaging
- 250mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- AS46102
- Product name
- 1-Ethynyl-4-(methylsulfonyl)benzene
- Purity
- 98%
- Packaging
- 250mg
- Price
- $111
- Updated
- 2021/12/16
- Product number
- W5557
- Product name
- 1-Ethynyl-4-(methylsulphonyl)-benzene
- Packaging
- 100mg
- Price
- $138
- Updated
- 2021/12/16
- Product number
- AS46102
- Product name
- 1-Ethynyl-4-(methylsulfonyl)benzene
- Purity
- 98%
- Packaging
- 1g
- Price
- $208
- Updated
- 2021/12/16
1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE Chemical Properties,Usage,Production
Synthesis
113854-19-6
340771-31-5
To a solution of tetrahydrofuran (450 mL) containing (4-methylsulfonylphenylethynyl)methylsilane (20.7 g, 82.0 mmol) was added tetrabutylammonium fluoride hydrate (8.80 g, 27.3 mmol). The reaction was immediately observed to change from yellow to red color. after 5 min, the reaction was completed and the solvent was subsequently removed under vacuum. Water was added to the residue and the resulting mixture was extracted three times with ethyl acetate. The combined organic layers were washed sequentially with water and brine, dried over magnesium sulfate, filtered and concentrated. The residue was suspended in dichloromethane and the insoluble material was filtered off. The filtrate was concentrated to give the crude product. Purification by fast chromatography (using a RediSep fast column with a silica gel particle size of 230-400 mesh and an eluent of 0-25% ethyl acetate in hexane solution) gave 1-ethynyl-4-methylsulfonylbenzene (10.7 g, 72% yield) as a yellow solid.
References
[1] Journal of Organic Chemistry, 2015, vol. 80, # 21, p. 10939 - 10954
[2] MedChemComm, 2018, vol. 9, # 3, p. 534 - 544
[3] Patent: WO2010/55005, 2010, A1. Location in patent: Page/Page column 107
[4] Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals, 1992, vol. 217, p. 19 - 24
[5] ChemPlusChem, 2015, vol. 80, # 6, p. 938 - 943
1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE Preparation Products And Raw materials
Raw materials
Preparation Products
1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE Suppliers
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View Lastest Price from 1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE manufacturers
- Product
- 1-ETHYNYL-4-(METHYLSULPHONYL)-BENZENE 340771-31-5
- Price
- US $50.00-500.00/KG
- Min. Order
- 1KG
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-10-13