ChemicalBook > CAS DataBase List > 1-METHYL-BIO

1-METHYL-BIO

Product Name
1-METHYL-BIO
CAS No.
667463-95-8
Chemical Name
1-METHYL-BIO
Synonyms
MEBIO;Me6BIO;1-METHYL-BIO;MeBIO, 10 mM in DMSO;GSK-3 INHIBITOR XIV, CONTROL;(2'Z,3'E)-6-Bromo-1-methylindirubin-3'-oxime;(2Z,3E)-6'-Bromo-3-(hydroxyimino)-1'-methyl-[2,3'-biindolinylidene]-2'-one;2H-Indol-2-one, 6-bromo-3-[(3E)-1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-1-methyl-, (3Z)-;Glycogen synthase kinase-3,CDK,GSK-3,Aryl Hydrocarbon Receptor (AhR),Glycogen synthase kinase 3,Inhibitor,inhibit,AhR,Agonist,Cyclin dependent kinase,Aryl Hydrocarbon Receptor,MeBIO
CBNumber
CB7850970
Molecular Formula
C17H12BrN3O2
Formula Weight
370.2
MOL File
667463-95-8.mol
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1-METHYL-BIO Property

storage temp. 
Store at +4°C
solubility 
Soluble to 10 mM in DMSO
form 
Powder
color 
Brown to reddish brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19573
Product name
MeBIO
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
19573
Product name
MeBIO
Purity
≥95%
Packaging
5mg
Price
$100
Updated
2024/03/01
Cayman Chemical
Product number
19573
Product name
MeBIO
Purity
≥95%
Packaging
10mg
Price
$169
Updated
2024/03/01
Tocris
Product number
3873
Product name
MeBIO
Purity
≥99%(HPLC)
Packaging
10
Price
$169
Updated
2021/12/16
TRC
Product number
M934565
Product name
MeBIO
Packaging
1mg
Price
$95
Updated
2021/12/16
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1-METHYL-BIO Chemical Properties,Usage,Production

Uses

MeBIO is an indirubin, which has been suggested to possess the structural basis for a potent and selective inhibitor of glycogen synthase kinase-3 (GSK3) and cyclin-dependent kinases.

IC 50

GSK-3: 44 μM (IC50); Cdk1/cyclin B: 55 μM (IC50); Cdk5/p25: >100 μM (IC50)

storage

Store at +4°C

1-METHYL-BIO Preparation Products And Raw materials

Raw materials

Preparation Products

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1-METHYL-BIO Suppliers

China 42 United Kingdom 1 United States 7 Global 50
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
8011
Advantage
55
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 18101056239
Email
3193328036@qq.com
Country
China
ProdList
29759
Advantage
68
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 13681763483
Email
product02@bidepharm.com
Country
China
ProdList
59936
Advantage
58

667463-95-8, 1-METHYL-BIORelated Search:


  • MEBIO
  • GSK-3 INHIBITOR XIV, CONTROL
  • 1-METHYL-BIO
  • (2'Z,3'E)-6-Bromo-1-methylindirubin-3'-oxime
  • Me6BIO
  • 2H-Indol-2-one, 6-bromo-3-[(3E)-1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-1-methyl-, (3Z)-
  • Glycogen synthase kinase-3,CDK,GSK-3,Aryl Hydrocarbon Receptor (AhR),Glycogen synthase kinase 3,Inhibitor,inhibit,AhR,Agonist,Cyclin dependent kinase,Aryl Hydrocarbon Receptor,MeBIO
  • (2Z,3E)-6'-Bromo-3-(hydroxyimino)-1'-methyl-[2,3'-biindolinylidene]-2'-one
  • MeBIO, 10 mM in DMSO
  • 667463-95-8