1-benzyl-2,3-dimethylguanidinium sulphate (2:1)
- Product Name
- 1-benzyl-2,3-dimethylguanidinium sulphate (2:1)
- CAS No.
- 114-85-2
- Chemical Name
- 1-benzyl-2,3-dimethylguanidinium sulphate (2:1)
- Synonyms
- Batel;Esbatal;Bendogen;Bethanid;EusManid;Hypersin;Tenathan;Betanidol;Benzaidin;BW 467C60
- CBNumber
- CB7890189
- Molecular Formula
- C10H17N3O4S
- Formula Weight
- 275.32
- MOL File
- 114-85-2.mol
1-benzyl-2,3-dimethylguanidinium sulphate (2:1) Property
- Melting point:
- >262oC (dec.)
- storage temp.
- Amber Vial, -20°C Freezer, Under inert atmosphere
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic, Light Sensitive
Safety
- Toxicity
- LD50 in mice (mg/kg): 12 i.v.; 150 i.p.; 260 s.c.; 520 by stomach intubation (Boura, Green)
N-Bromosuccinimide Price
- Product number
- B328910
- Product name
- BethanidineSulfate
- Packaging
- 500mg
- Price
- $690
- Updated
- 2021/12/16
- Product number
- FB32172
- Product name
- Bethanidine sulfate
- Packaging
- 5mg
- Price
- $59
- Updated
- 2021/12/16
- Product number
- FB32172
- Product name
- Bethanidine sulfate
- Packaging
- 10mg
- Price
- $94
- Updated
- 2021/12/16
- Product number
- FB32172
- Product name
- Bethanidine sulfate
- Packaging
- 25mg
- Price
- $170
- Updated
- 2021/12/16
- Product number
- FB32172
- Product name
- Bethanidine sulfate
- Packaging
- 50mg
- Price
- $270
- Updated
- 2021/12/16
1-benzyl-2,3-dimethylguanidinium sulphate (2:1) Chemical Properties,Usage,Production
Originator
Bendogen,Lagap Pharmaceuticals SA
Uses
Antihypertensive.
Manufacturing Process
A mixture of 2-bromobenzylamine (12.5 g) and S-methylthiouronium sulfate (10 g) in water (20 ml) was heated for 1.5 hours on a steam bath in a hood, during which methylmercaptan escaped (as evidenced by a foul odour). The reaction mixture was then cooled and diluted with ethanol (100 ml). A colourless solid of 2-bromobenzylguanidine sulfate was separeted, and washed with ethanol. This solid melted at 230-232°C; it was recrystallized from water and then melted at 247-248°C. By action of a basic agent the salt obtained may be converted into free base.
brand name
Tenathan (Robins).
Therapeutic Function
Antihypertensive
Safety Profile
Poison by intraperitoneal,subcutaneous, and intravenous routes. Moderately toxicby ingestion. When heated todecomposition it emits toxic fumes of NOx and SOx.
Safety Profile
Poison by subcutaneous andintraperitoneal routes. Moderately toxic by ingestion.When heated to decomposition it emits toxic fumes ofSOx and NOx.
1-benzyl-2,3-dimethylguanidinium sulphate (2:1) Preparation Products And Raw materials
Raw materials
Preparation Products
1-benzyl-2,3-dimethylguanidinium sulphate (2:1) Suppliers
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