ChemicalBook > CAS DataBase List > 1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride

1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride

Product Name
1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride
CAS No.
5424-37-3
Chemical Name
1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride
Synonyms
Surfen;Surfen (NSC-12155);Surfen dihydrochloride;NSC-12155 (surfen hydrate);Aminoquinuride hydrochloride;Aminokinuride dihydrochloride;Aminoquinuride dihydrochloride;Aminoquincarbamide dihydrochloride;1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride;1,3-bis(4-amino-2-methylquinolin-6-yl)urea, dihydrochloride
CBNumber
CB7922378
Molecular Formula
C21H22Cl2N6O
Formula Weight
445.34498
MOL File
5424-37-3.mol
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1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
color 
Off-white to gray
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26670
Product name
Surfen (hydrochloride)
Purity
≥98%
Packaging
5mg
Price
$109
Updated
2026/04/30
Cayman Chemical
Product number
26670
Product name
Surfen (hydrochloride)
Purity
≥98%
Packaging
10mg
Price
$174
Updated
2026/04/30
Cayman Chemical
Product number
26670
Product name
Surfen (hydrochloride)
Purity
≥98%
Packaging
25mg
Price
$382
Updated
2026/04/30
Biorbyt Ltd
Product number
orb1701546
Product name
Surfen dihydrochloride
Purity
97.08%
Packaging
2mg
Price
$90
Updated
2026/05/06
Biorbyt Ltd
Product number
orb1701546
Product name
Surfen dihydrochloride
Purity
97.08%
Packaging
5mg
Price
$130
Updated
2026/05/06
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1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride Chemical Properties,Usage,Production

Uses

Surfen dihydrochloride is a potent HS (heparan sulfate) antagonist. Surfen binds to glycosaminoglycans. Surfen neutralizes the anticoagulant activity of both unfractionated and low molecular weight heparins. Surfen affects sulfation of heparin and inhibits degradation by heparin lyases. Surfen inhibits FGF2 binding and signaling. Surfen inhibits cell attachment, and virus infection[1].

IC 50

FGFR2: 5 μM (IC50); HSV-1

storage

Store at -20°C

References

[1] Schuksz M, et al. Surfen, a small molecule antagonist of heparan sulfate. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13075-80. DOI:10.1073/pnas.0805862105

1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride Suppliers

China 20 United Kingdom 1 United States 2 Global 23
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
89686
Advantage
60
Shanghai Rechem science Co., Ltd.
Tel
021-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2970
Advantage
58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32466
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-87569266 +86-17392581500
Fax
029-88380327
Email
1015@dideu.com
Country
China
ProdList
3992
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
29717
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310 15002144251
Email
marketing@tsbiochem.com
Country
China
ProdList
24955
Advantage
58
Shaanxi Dideu Newmaterial Co., Ltd.
Tel
029-63373950 17392216152
Email
1050@dideu.com
Country
China
ProdList
9999
Advantage
58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd
Tel
021-59167510 18117107507
Email
vip@med-life.cn
Country
China
ProdList
5001
Advantage
58

5424-37-3, 1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochlorideRelated Search:

6-Aminoquinoline 4,6-DIAMINO-2-METHYL-QUINOLINE 1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride 1,3-di-6-quinolylurea Aminoquinuride 6-AMINOQUINOLINE HYDROCHLORIDE

  • Aminoquinuride hydrochloride
  • Aminoquincarbamide dihydrochloride
  • NSC-12155 (surfen hydrate)
  • 1,3-bis(4-amino-2-methyl-6-quinolyl)urea dihydrochloride
  • Surfen
  • Surfen dihydrochloride
  • Surfen (NSC-12155)
  • 1,3-bis(4-amino-2-methylquinolin-6-yl)urea, dihydrochloride
  • Aminoquinuride dihydrochloride
  • Aminokinuride dihydrochloride
  • Aminokinuride dihydrochloride|||Aminoquinuride dihydrochloride|||NSC-12155|||Aminokinuride 2HCl|||Aminoquinuride 2HCl
  • 5424-37-3