ChemicalBook > CAS DataBase List > 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
- Product Name
- 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
- CAS No.
- 74853-07-9
- Chemical Name
- 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
- Synonyms
- Posaconazole inter-5;Posazonazole Intermediate 5;2,4-Dihydro-4-[4-[4-(4-methoxypheny;Posaconazole Methoxy Triazole Impurity;4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-4H-1,2,4-triazol-3-ol;4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one;4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-1H-1,2,4-triazol-5-one;4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one;4-[4-[4-(4-Methoxyphenyl)piperazino]phenyl]-3,4-dihydro-2H-1,2,4-triazole-3-one;2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
- CBNumber
- CB7930766
- Molecular Formula
- C19H21N5O2
- Formula Weight
- 351.4
- MOL File
- 74853-07-9.mol
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2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Property
- Melting point:
- 270-277°C (dec.)
- Density
- 1.30±0.1 g/cm3(Predicted)
- vapor pressure
- 0-0Pa at 20-25℃
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO (Slightly, Heated)
- form
- Solid:particulate/powder
- pka
- 10.16±0.20(Predicted)
- LogP
- 2.3 at pH7
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
TRC
- Product number
- M266245
- Product name
- 4-{[4-(4-Methyloxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one
- Packaging
- 10mg
- Price
- $55
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0070321
- Product name
- 2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)PIPERAZIN-1-YL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $704.55
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0070321
- Product name
- 2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)PIPERAZIN-1-YL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $1593.9
- Updated
- 2021/12/16
Alichem
- Product number
- 74853079
- Product name
- 4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one
- Packaging
- 250mg
- Price
- $235.62
- Updated
- 2021/12/16
Chemenu
- Product number
- CM169541
- Product name
- 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
- Purity
- 95%
- Packaging
- 1g
- Price
- $557
- Updated
- 2021/12/16
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2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Uses
4-{[4-(4-Methyloxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one, is an intermediate for the synthesis of Itraconazole (I937500), an Antifungal.
2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Preparation Products And Raw materials
Raw materials
Preparation Products
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74853-07-9, 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-oneRelated Search:
Posaconazole
Posaconazole Diastereoisomer 12
Posaconazole-d4
Posaconazole DiastereoisoMer interMediate 2
1H-1,2,4-TRIAZOLE, 1-[[(2S)-2-(2,4-DIFLUOROPHENYL)OXIRANYL]METHYL]-
Posaconazole-d5
2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one
2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
Itraconazole
HYDROXY ITRACONAZOLE
SAPERCONAZOLE
KETO ITRACONAZOLE
3H-1,2,4-TRIAZOL-3-ONE, 2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]PHENYL]-2-(1-METHYLPROPYL)-, (S)-
ITRACONAZOLE-5-METHYL-2-ISOPENTANE
MITRATAPID
BENZYL HYDROXY ITRACONAZOLE
3H-1,2,4-TRIAZOL-3-ONE, 2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)-1-PIPERAZINYL]PHENYL]-2-(1-METHYLPROPYL)-, (R)-
2-SEC-BUTYL-D5-4-(4-[4-(4-METHYLOXY-PHENYL)-PIPERAZIN-1-YL]-PHENYL)-2,4-DIHYDRO-[1,2,4]-TRIAZOL-3-ONE