ChemicalBook > CAS DataBase List > 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one

2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one

Product Name
2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
CAS No.
74853-07-9
Chemical Name
2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
Synonyms
Posaconazole inter-5;Posazonazole Intermediate 5;2,4-Dihydro-4-[4-[4-(4-methoxypheny;Posaconazole Methoxy Triazole Impurity;4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-4H-1,2,4-triazol-3-ol;4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one;4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-1H-1,2,4-triazol-5-one;4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one;4-[4-[4-(4-Methoxyphenyl)piperazino]phenyl]-3,4-dihydro-2H-1,2,4-triazole-3-one;2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
CBNumber
CB7930766
Molecular Formula
C19H21N5O2
Formula Weight
351.4
MOL File
74853-07-9.mol
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2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Property

Melting point:
270-277°C (dec.)
Density 
1.30±0.1 g/cm3(Predicted)
vapor pressure 
0-0Pa at 20-25℃
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO (Slightly, Heated)
form 
Solid:particulate/powder
pka
10.16±0.20(Predicted)
LogP
2.3 at pH7
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M266245
Product name
4-{[4-(4-Methyloxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one
Packaging
10mg
Price
$55
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0070321
Product name
2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)PIPERAZIN-1-YL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE
Purity
95.00%
Packaging
10MG
Price
$704.55
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0070321
Product name
2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)PIPERAZIN-1-YL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE
Purity
95.00%
Packaging
100MG
Price
$1593.9
Updated
2021/12/16
Alichem
Product number
74853079
Product name
4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one
Packaging
250mg
Price
$235.62
Updated
2021/12/16
Chemenu
Product number
CM169541
Product name
2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
Purity
95%
Packaging
1g
Price
$557
Updated
2021/12/16
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2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

4-{[4-(4-Methyloxyphenyl)-piperazin-1-yl]-phenyl}-2,4-dihydro-[1,2,4]-triazol-3-one, is an intermediate for the synthesis of Itraconazole (I937500), an Antifungal.

2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one Suppliers

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74853-07-9, 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-oneRelated Search:


  • 2,4-dihydro-4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-3H-1,2,4-triazol-3-one
  • 4-[4-[4-(4-Methoxyphenyl)piperazino]phenyl]-3,4-dihydro-2H-1,2,4-triazole-3-one
  • Posaconazole inter-5
  • 4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-1H-1,2,4-triazol-5-one
  • 2,4-DIHYDRO-4-[4-[4-(4-METHOXYPHENYL)PIPERAZIN-1-YL]PHENYL]-3H-1,2,4-TRIAZOL-3-ONE(WXC08779)
  • 4-[4-[4-(4-methoxyphenyl)piperazin-1-yl]phenyl]-1H-1,2,4-triazol-5-one
  • 3H-1,2,4-Triazol-3-one,2,4-dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-
  • 4-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one
  • 2,4-Dihydro-4-[4-[4-(4-methoxypheny
  • Posaconazole Methoxy Triazole Impurity
  • 2,4-Dihydro-4-[4-[4-(4-methoxyphenyl)-1-piperazinyl]phenyl]-3H-1,2,4-triazole-3- one
  • Posazonazole Intermediate 5
  • 4-(4-(4-(4-Methoxyphenyl)piperazin-1-yl)phenyl)-4H-1,2,4-triazol-3-ol
  • 74853-07-9
  • Intermediates & Fine Chemicals
  • Pharmaceuticals