ChemicalBook > CAS DataBase List > 4'-Bromo-3'-methylacetophenone

4'-Bromo-3'-methylacetophenone

Product Name
4'-Bromo-3'-methylacetophenone
CAS No.
37074-40-1
Chemical Name
4'-Bromo-3'-methylacetophenone
Synonyms
NSC 405623;Fluralaner-003;Fluralaner Impurity 29;3-Methyl-4-bromoacetophenone;4-Bromo-3-methylacetophenone;4'-Bromo-3'-methylacetophenone;4'-BROMO-3'-METHYLACETOPHENONE;Ethanone, 1-(4-broMo-3-Methylphenyl)-
CBNumber
CB7947102
Molecular Formula
C9H9BrO
Formula Weight
213.07
MOL File
37074-40-1.mol
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4'-Bromo-3'-methylacetophenone Property

Melting point:
31-32 °C
Boiling point:
157-159 °C(Press: 19 Torr)
Density 
1.388±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
fused solid
color 
Pale lemon
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Safety

HS Code 
2914390090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TRC
Product number
B697460
Product name
1-(4-Bromo-3-methylphenyl)ethanone
Packaging
500mg
Price
$60
Updated
2021/12/16
TRC
Product number
B697460
Product name
1-(4-Bromo-3-methylphenyl)ethanone
Packaging
1g
Price
$70
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB70251
Product name
4'-Bromo-3'-methylacetophenone, 98%
Packaging
2g
Price
$90
Updated
2021/12/16
Apolloscientific
Product number
OR400663
Product name
4’-Bromo-3’-methylacetophenone
Packaging
1g
Price
$112
Updated
2021/12/16
SynQuest Laboratories
Product number
2717-9-33
Product name
4?-Bromo-3?-methylacetophenone
Packaging
1g
Price
$124
Updated
2021/12/16
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4'-Bromo-3'-methylacetophenone Chemical Properties,Usage,Production

Uses

4'-Bromo-3'-methylacetophenone is a versatile building block that is used in the synthesis of many complex compounds. It can be used as a reactant, reagent, or speciality chemical.

Synthesis

A solution of 4-bromo-3-methylbenzaldehyde (4 g, 20 mmol) in dry tetrahydrofuran (40 mL) was cooled to 0??C under nitrogen atmosphere, and then methyl magnesium bromide (20 mL, 1N in tetrahydrofuran) was added dropwise. The ice bath was removed, and the mixture was stirred for 2 hours. Ammonium chloride aqueous (40 mL) was added and the mixture was extracted with dichloromethane (20 mL * 3). The organic phase was dried by sodium sulphate, filtered and concentrated to give a residue. The residue was purified by column chromatography (silica gel, petroleum ether/ethyl acetate = 5:1) to give 1-(4-bromo-3-methylphenyl)ethanol. Colorless oil, yield 4.0 g, 93%. Pyridinium chlorochromate (48 g, 223 mmol) was added to a solution of 1-(4-bromo-3-methylphenyl)ethanol (31.9 g, 148 mmol) in dichloromethane (800 mL). The mixture was stirred at room temperature for 2 hours. The mixture was concentrated to give a residue. The residue was purified by column chromatography (silica gel, petroleum ether/ethyl acetate = 25:1) to give 4'-Bromo-3'-methylacetophenone. Yield 27.3 g, 87%.
Figure Synthesis of 4'-Bromo-3'-methylacetophenone

4'-Bromo-3'-methylacetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

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4'-Bromo-3'-methylacetophenone Suppliers

A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 4'-Bromo-3'-methylacetophenone manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
4'-Bromo-3'-methylacetophenone 37074-40-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-07
Career Henan Chemical Co
Product
4'-Bromo-3'-methylacetophenone 37074-40-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-12