METHIOTHEPIN MESYLATE SEROTININ 5-HT(1) ANT

Product Name: METHIOTHEPIN MESYLATE SEROTININ 5-HT(1) ANT
CAS No.: 74611-28-2
Chemical Name: METHIOTHEPIN MESYLATE SEROTININ 5-HT(1) ANT
Synonyms: Ro 8-6837 mesylate;Metitepine mesylate salt;methiothepin mesylate salt;Methiothepin mesylate, 10 mM in DMSO;METHIOTHEPIN MESYLATE SEROTININ 5-HT(1) ANT;1-[10,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methylpiperazine mesylate salt;1-Methyl-4-(8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine methanesulfonate;Methiothepin mesylate 1-Methyl-4-(3-methylsulfanyl-5,6- dihydrobenzo[b][1]benzothiepin-5-yl)piperazine;Metitepine mesylate salt, 1-[10,11-Dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methylpiperazine mesylate salt;Ro 8-6837,inhibit,Methiothepin mesylate,Serotonin Receptor,Metitepine,Methiothepin,5-HT Receptor,5-hydroxytryptamine Receptor,Inhibitor
CBNumber: CB7972919
Molecular Formula: C20H24N2S2CH3SO3H
Formula Weight: 0
MOL File: 74611-28-2.mol

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METHIOTHEPIN MESYLATE SEROTININ 5-HT(1) ANT Property

storage temp.: Store at -20°C
solubility: H2O: soluble13mg/mL
form: solid
color: white
Water Solubility: H2O: 13mg/mL

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M149
Product name: Methiothepin mesylate salt
Purity: ≥98% (HPLC), solid
Packaging: 100mg
Price: $136
Updated: 2025/07/31

Sigma-Aldrich

Product number: M149
Product name: Methiothepin mesylate salt
Purity: ≥98% (HPLC), solid
Packaging: 250mg
Price: $210.7
Updated: 2025/07/31

TRC

Product number: M260628
Product name: Methiothepin mesylate salt
Packaging: 100mg
Price: $80
Updated: 2021/12/16

ChemScene

Product number: CS-0030713
Product name: Methiothepinmesylate
Purity: 99.32%
Packaging: 10mg
Price: $60
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008327
Product name: METHIOTHEPIN MESYLATE SALT
Purity: 95.00%
Packaging: 100MG
Price: $642.52
Updated: 2021/12/16

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METHIOTHEPIN MESYLATE SEROTININ 5-HT(1) ANT Chemical Properties,Usage,Production

Uses

Methiothepin mesylate salt has been used to explore the relationship between circulating cells and the niche. It has also been used in serotonin (5-HT) and antagonists in vivo bioassays and in in vivo antagonist and lipopolysaccharide stimulations.

General Description

Methiothepin belongs to a new class of dibenzothiophenes. Methiothepin possesses neuroleptic activity.

Biochem/physiol Actions

Methiothepin mesylate salt is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors.

IC 50

5-HT_1A Receptor: 7.10 (pKd); 5-HT_1B Receptor: 7.28 (pKd); 5-HT_1C Receptor: 7.56 (pKd); 5-HT_1D Receptor: 6.99 (pKd); 5-HT_5A Receptor: 7.0 (pKd); 5-HT_5B Receptor: 7.8 (pKd); 5-HT₆ Receptor: 8.74 (pKd); 5-HT₇ Receptor: 8.99 (pKd); 5-HT_2A Receptor: 8.50 (pKi); 5-HT_2B Receptor: 8.68 (pKi); 5-HT_2C Receptor: 8.35 (pKi)

METHIOTHEPIN MESYLATE SEROTININ 5-HT(1) ANT Preparation Products And Raw materials

Raw materials

Preparation Products

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METHIOTHEPIN MESYLATE SEROTININ 5-HT(1) ANT Suppliers

China 33 Switzerland 1 United States 6 Global 40

Sigma-Aldrich

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Beijing Aomi Jiade Pharmaceutical Technology Co., Ltd

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74611-28-2, METHIOTHEPIN MESYLATE SEROTININ 5-HT(1) ANTRelated Search:

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METHIOTHEPIN MESYLATE SEROTININ 5-HT(1) ANT

1-[10,11-dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methylpiperazine mesylate salt

methiothepin mesylate salt

Metitepine mesylate salt, 1-[10,11-Dihydro-8-(methylthio)dibenzo[b,f]thiepin-10-yl]-4-methylpiperazine mesylate salt

Metitepine mesylate salt

Ro 8-6837 mesylate

Methiothepin mesylate 1-Methyl-4-(3-methylsulfanyl-5,6- dihydrobenzo[b][1]benzothiepin-5-yl)piperazine

1-Methyl-4-(8-(methylthio)-10,11-dihydrodibenzo[b,f]thiepin-10-yl)piperazine methanesulfonate

Ro 8-6837,inhibit,Methiothepin mesylate,Serotonin Receptor,Metitepine,Methiothepin,5-HT Receptor,5-hydroxytryptamine Receptor,Inhibitor

Methiothepin mesylate, 10 mM in DMSO

74611-28-2

CH4O3SC20H24N2S2

C20H24N2S2CH3SO3H

Inhibitors