Vocacapsaicin
- Product Name
- Vocacapsaicin
- CAS No.
- 1931116-86-7
- Chemical Name
- Vocacapsaicin
- Synonyms
- CA-008;Vocacapsaicin;1-Piperidinecarboxylic acid, 2-[(methylamino)methyl]-, 2-methoxy-4-[[[(6E)-8-methyl-1-oxo-6-nonen-1-yl]amino]methyl]phenyl ester
- CBNumber
- CB79743914
- Molecular Formula
- C26H41N3O4
- Formula Weight
- 459.62
- MOL File
- 1931116-86-7.mol
Vocacapsaicin Property
- Boiling point:
- 632.9±55.0 °C(Predicted)
- Density
- 1.063±0.06 g/cm3(Predicted)
- pka
- 15.46±0.46(Predicted)
Vocacapsaicin Chemical Properties,Usage,Production
Description
Vocacapsaicin (CA-008), a proagent of Capsaicin, is a first-in-class non-opioid TRPV1 agonist. Vocacapsaicin can provide meaningful and long-lasting pain relief.
Mode of action
Vocacapsaicin(CA-008, Conentric Analgesics) – an investigational TRPV agonist being studied for long-lasting pain – works through the same TRPV1 agonism mechanism but its localized delivery is thought to minimize activation of a large array of neurons, such as capsaicin topical products.
References
[1] TARRA KNOTTS. Pharmacokinetics and local tissue response to local instillation of vocacapsaicin, a novel capsaicin prodrug, in rat and rabbit osteotomy models[J]. Journal of Orthopaedic Research?, 2022, 40 10: 2281-2293. DOI:10.1002/jor.25271.
[2]. Olivia Higgins, et al. Analgesics of the Future: The Potential of Vocacapsaicin Injections for Knee Pain. 12 Articles in Volume 21, Issue #2.
Vocacapsaicin Preparation Products And Raw materials
Raw materials
Preparation Products
Vocacapsaicin Suppliers
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 19703
- Advantage
- 58