4-BROMO-ISOQUINOLINE 2-OXIDE

Product Name: 4-BROMO-ISOQUINOLINE 2-OXIDE
CAS No.: 3749-21-1
Chemical Name: 4-BROMO-ISOQUINOLINE 2-OXIDE
Synonyms: Fampridine Impurity 58;4-Bromoisoquinoline N-oxide;4-BROMO-ISOQUINOLINE 2-OXIDE;Isoquinoline, 4-bromo-, 2-oxide;4-bromo-2-oxidoisoquinolin-2-ium
CBNumber: CB81010600
Molecular Formula: C9H6BrNO
Formula Weight: 224.05
MOL File: 3749-21-1.mol

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4-BROMO-ISOQUINOLINE 2-OXIDE Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

AK Scientific

Product number: 7583CD
Product name: 4-Bromoisoquinoline2-oxide
Packaging: 250mg
Price: $151
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0104732
Product name: 4-BROMOISOQUINOLINE 2-OXIDE
Purity: 95.00%
Packaging: 250MG
Price: $280.35
Updated: 2021/12/16

Crysdot

Product number: CD65000068
Product name: 4-Bromoisoquinoline2-oxide
Purity: 95%
Packaging: 250mg
Price: $58
Updated: 2021/12/16

Crysdot

Product number: CD65000068
Product name: 4-Bromoisoquinoline2-oxide
Purity: 95%
Packaging: 1g
Price: $148
Updated: 2021/12/16

Crysdot

Product number: CD65000068
Product name: 4-Bromoisoquinoline2-oxide
Purity: 95%
Packaging: 5g
Price: $445
Updated: 2021/12/16

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4-BROMO-ISOQUINOLINE 2-OXIDE Chemical Properties,Usage,Production

Synthesis

1532-97-4

3749-21-1

General procedure for the synthesis of 4-bromoisoquinoline 2-oxide from 4-bromoisoquinoline (Compound 13A): a chloroform (100 mL) solution of 4-bromoisoquinoline (4.16 g, 18.6 mmol) was added dropwise to a chloroform (100 mL) solution of 70% mCPBA (12.4 g, 50.3 mmol) over a period of 1 h at room temperature. The reaction mixture was stirred at room temperature for 18 h. The reaction mixture was washed with 1N NaOH solution (2 x 150 mL), dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to give an off-white solid compound 13A (4.23 g, 94% yield).1H NMR (400 MHz, CDCl3) δ 8.71 (s, 1 H), 8.43 (s, 1 H), 8.09 (d, 1 H) , J = 8 Hz), 7.70 (m, 3H).

References

[1] Patent: US2004/19063, 2004, A1
[2] Patent: US2004/181064, 2004, A1
[3] Journal of Medicinal Chemistry, 1995, vol. 38, # 21, p. 4234 - 4243
[4] Chemical Communications, 2018, vol. 54, # 32, p. 3977 - 3980
[5] Organic and Biomolecular Chemistry, 2016, vol. 14, # 24, p. 5820 - 5825

4-BROMO-ISOQUINOLINE 2-OXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BROMO-ISOQUINOLINE 2-OXIDE Suppliers

China 37 Germany 1 India 1 The Netherlands 1 United States 3 Global 43

J & K SCIENTIFIC LTD.

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Synchem OHG

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View Lastest Price from 4-BROMO-ISOQUINOLINE 2-OXIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4-BROMO-ISOQUINOLINE 2-OXIDE 3749-21-1
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20t
Release date: 2024-07-14

3749-21-1, 4-BROMO-ISOQUINOLINE 2-OXIDERelated Search:

3-Bromopyridine 1-oxide 4-Bromoisoquinoline 4-BROMO-ISOQUINOLINE 2-OXIDE ISOQUINOLINE N-OXIDE

4-BROMO-ISOQUINOLINE 2-OXIDE

4-Bromoisoquinoline N-oxide

4-bromo-2-oxidoisoquinolin-2-ium

Isoquinoline, 4-bromo-, 2-oxide

Fampridine Impurity 58

3749-21-1