ChemicalBook > CAS DataBase List > 2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE

2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE

Product Name
2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE
CAS No.
447406-52-2
Chemical Name
2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE
Synonyms
2-(3-ethylphenyl)thiazole-5-carbaldehyde;2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE;2-[4-(trifluoromethyl)phenyl]-5-thiazolecarboxaldehyde;5-Thiazolecarboxaldehyde, 2-[4-(trifluoromethyl)phenyl]-;2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE, 95+%;2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carbaldehyde
CBNumber
CB8104492
Molecular Formula
C11H6F3NOS
Formula Weight
257.23
MOL File
447406-52-2.mol
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2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE Property

storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
COR0001534
Product name
2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE
Purity
95.00%
Packaging
250MG
Price
$203.7
Updated
2021/12/16
Ark Pharm
Product number
P000217742
Product name
2-(4-Trifluoromethylphenyl)thiazole-5-carbaldehyde
Purity
95+%
Packaging
5g
Price
$332
Updated
2021/12/16
Matrix Scientific
Product number
071670
Product name
2-(4-Trifluoromethylphenyl)thiazole-5-carbaldehyde
Purity
95+%
Packaging
1g
Price
$462
Updated
2021/12/16
AK Scientific
Product number
W6346
Product name
2-(4-Trifluoromethylphenyl)thiazole-5-carbaldehyde
Packaging
5g
Price
$506
Updated
2021/12/16
Ark Pharm
Product number
P000217742
Product name
2-(4-Trifluoromethylphenyl)thiazole-5-carbaldehyde
Purity
95+%
Packaging
1g
Price
$102
Updated
2021/12/16
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2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE Chemical Properties,Usage,Production

Synthesis

464192-28-7

128796-39-4

447406-52-2

2-Bromo-5-formylthiazole (525 mg, 2.73 mmol) and 4-trifluoromethylphenylboronic acid (519 mg, 2.73 mmol), catalyzed by tetrakis(triphenylphosphine)palladium(0) (95 mg, 0.082 mmol), were mixed with an aqueous solution of 2 M Na2CO3 (5.5 mL, 10.94 mmol) in dioxane (8 mL) The reaction was carried out at reflux for 20 hours. After completion of the reaction, it was cooled to room temperature and extracted with EtOAc and water by partitioning. After separation of the organic phase, it was washed with water and brine sequentially. The organic phase was dried over anhydrous Na2SO4 and concentrated under reduced pressure. The crude product was purified by column chromatography with EtOAc/hexane as eluent to afford the target compound 2-(4-trifluoromethylphenyl)thiazole-5-carbaldehyde as a yellow solid (145 mg, 21% yield).

References

[1] Patent: US2007/244094, 2007, A1. Location in patent: Page/Page column 51-52

2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE Suppliers

Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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Pure Chemistry Scientific Inc.
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Hubei Jusheng Technology Co.,Ltd
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Amadis Chemical Company Limited
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Shanghai Civic Chemical Technology Co., Ltd.
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Amatek Scientific Co. Ltd.
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Capot Chemical Co.,Ltd.
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Aikon International Limited
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025-58859352 18068836627
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Dayang Chem (Hangzhou) Co.,Ltd.
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+86-0571-88938639 +8617705817739
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View Lastest Price from 2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE manufacturers

Career Henan Chemica Co
Product
2-(4-TRIFLUOROMETHYLPHENYL)THIAZOLE-5-CARBALDEHYDE 447406-52-2
Price
US $0.01/KG
Min. Order
1KG
Purity
95%-99%
Supply Ability
1kg; 5kg; 10kg
Release date
2020-10-27