Pyrazinemethanol, alpha-methyl- (9CI)
- Product Name
- Pyrazinemethanol, alpha-methyl- (9CI)
- CAS No.
- 94777-52-3
- Chemical Name
- Pyrazinemethanol, alpha-methyl- (9CI)
- Synonyms
- 1-(2-Pyrazinyl)-1-ethanol;2-(1-Hydroxyethyl)pyrazine;1-(pyrazin-2-yl)ethan-1-ol;alpha-Methylpyrazinemethanol;2-Pyrazinemethanol, α-methyl-;Pyrazinemethanol, alpha-methyl- (9CI)
- CBNumber
- CB81056109
- Molecular Formula
- C6H8N2O
- Formula Weight
- 124.14
- MOL File
- 94777-52-3.mol
Pyrazinemethanol, alpha-methyl- (9CI) Property
- Boiling point:
- 234℃
- Density
- 1.160
- Flash point:
- 96℃
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- Colorless to light yellow Liquid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P840938
- Product name
- 1-(Pyrazin-2-yl)ethanol
- Packaging
- 50mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- P840938
- Product name
- 1-(Pyrazin-2-yl)ethanol
- Packaging
- 25mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CHM0104819
- Product name
- 1-(PYRAZIN-2-YL)ETHAN-1-OL
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $852.55
- Updated
- 2021/12/16
- Product number
- 5979CC
- Product name
- 1-Pyrazin-2-yl-ethanol
- Packaging
- 1g
- Price
- $853
- Updated
- 2021/12/16
- Product number
- Z1036
- Product name
- a-methyl-2-Pyrazinemethanol
- Purity
- 97.00%
- Packaging
- 1G
- Price
- $1530
- Updated
- 2021/12/16
Pyrazinemethanol, alpha-methyl- (9CI) Chemical Properties,Usage,Production
Synthesis
22047-25-2
94777-52-3
General method: Catalyst (0.1 mol %) and potassium hydroxide (1 mmol) were dissolved in isopropanol (4 mL). To this solution 2-acetylpyrazine (1 mmol) was added and the mixture was heated to reflux (82 °C). The progress of the reaction was monitored by gas chromatography (GC) periodically during the reaction. Upon completion of the reaction, the mixture was cooled to room temperature and filtered through a silica gel or alumina column using a 50% ethyl acetate-hexane mixture as the eluent. The eluate was collected, concentrated and analyzed by gas chromatography (GC) and/or gas chromatography-mass spectrometry (GC-MS).
References
[1] Journal of Organic Chemistry, 1992, vol. 57, # 17, p. 4756 - 4761
[2] Organic Letters, 2005, vol. 7, # 12, p. 2505 - 2508
[3] Bioscience, Biotechnology and Biochemistry, 2011, vol. 75, # 6, p. 1055 - 1060
[4] Organic and Biomolecular Chemistry, 2015, vol. 13, # 6, p. 1768 - 1777
[5] Organic and Biomolecular Chemistry, 2017, vol. 15, # 43, p. 9169 - 9175