Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI)
- Product Name
- Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI)
- CAS No.
- 90724-57-5
- Chemical Name
- Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI)
- Synonyms
- 3-Methyl-1H-pyrrole-2-carboxylicacid;3-Methylpyrrole-2-carboxylic Acid;3-Methyl-1H-pyrrol-2-carboxylic acid;Pyrrole-2-carboxylic acid, 3-methyl-;Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI)
- CBNumber
- CB81064355
- Molecular Formula
- C6H7NO2
- Formula Weight
- 125.13
- MOL File
- 90724-57-5.mol
Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI) Property
- Melting point:
- 200 °C (decomp)
- Boiling point:
- 322.4±22.0 °C(Predicted)
- Density
- 1.295±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 5.10±0.50(Predicted)
- Appearance
- White to gray Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T325260
- Product name
- 3-METHYL-1H-PYRROLE-2-CARBOXYLIC ACID
- Purity
- AldrichCPR
- Packaging
- 5MG
- Price
- $148
- Updated
- 2025/07/31
- Product number
- M336565
- Product name
- 3-Methyl-1H-pyrrole-2-carboxylicAcid
- Packaging
- 250mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- W9332
- Product name
- 3-Methyl-1H-pyrrole-2-carboxylicacid
- Packaging
- 250mg
- Price
- $141
- Updated
- 2021/12/16
- Product number
- 4H21-1-CL
- Product name
- 3-Methyl-1H-pyrrole-2-carboxylic acid
- Packaging
- 1g
- Price
- $378
- Updated
- 2021/12/16
- Product number
- CHM0150130
- Product name
- 3-METHYL-1H-PYRROLE-2-CARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.29
- Updated
- 2021/12/16
Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI) Chemical Properties,Usage,Production
Synthesis
40611-69-6
90724-57-5
General procedure for the synthesis of 3-methyl-1H-pyrrole-2-carboxylic acid from methyl 3-methyl-1H-pyrrole-2-carboxylate: 1. dissolve methyl 3-methyl-1H-pyrrole-2-carboxylate (2.0 g, 14.37 mmol, purchased from Otava Chemicals, Catalog No. 1056278) in 50 mL of methanol. 2. 21.5 mL of 2N aqueous sodium hydroxide was added to the solution. 3. The reaction mixture was stirred overnight at room temperature, then warmed to 60 °C and continued stirring for 20 hours. 4. Upon completion of the reaction, the methanol was removed by vacuum evaporation. 5. The remaining aqueous solution was neutralized with 21.5 mL of 2N hydrochloric acid solution. 6. The product was extracted using a 95:5 chloroform/methanol mixture. 7. The organic phase was washed with brine, dried over magnesium sulfate, filtered and evaporated in vacuum. 8. 1.38 g (77% yield) of the target compound 3-methyl-1H-pyrrole-2-carboxylic acid was obtained as a brown solid. LRMS (m/z): 126 (M + 1)+. 1H NMR (400 MHz, DMSO) δ 12.06 (s, 1H), 11.30 (s, 1H), 6.84-6.75 (m, 1H), 6.02-5.93 (m, 1H), 2.24 (s, 3H).
References
[1] Patent: WO2012/146666, 2012, A1. Location in patent: Page/Page column 105
[2] Patent: EP2518070, 2012, A1. Location in patent: Page/Page column 44
[3] Patent: WO2014/60431, 2014, A1. Location in patent: Page/Page column 91
[4] Patent: WO2014/60432, 2014, A1. Location in patent: Page/Page column 122; 123
Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI) Preparation Products And Raw materials
Raw materials
Preparation Products
Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI) Suppliers
- Tel
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- Fax
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- sales@ajchem.in
- Country
- India
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View Lastest Price from Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI) manufacturers
- Product
- Pyrrole-2-carboxylic acid, 3-methyl- (6CI,7CI) 90724-57-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2020-01-08