CYCLO(ARG-GLY-ASP-D-PHE-VAL)

Product Name: CYCLO(ARG-GLY-ASP-D-PHE-VAL)
CAS No.: 137813-35-5
Chemical Name: CYCLO(ARG-GLY-ASP-D-PHE-VAL)
Synonyms: cRGDfV;EMD 66203;CYCLO(RGDD-FV);cyclo(RGD-DPhe-V);EMD 66203, c(RGDfV);RGDFV PEPTIDE, CYCLIC;CYCLO(ARG-GLY-ASP-D-PHE-VAL);Cyclo(Arg-Gls-Asp-D-Phe-Val);Cyclo(-Arg-Gly-Asp-D-Phe-Val) trifluoroacetate salt;Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-valyl)
CBNumber: CB8106724
Molecular Formula: C26H38N8O7
Formula Weight: 574.63
MOL File: 137813-35-5.mol

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CYCLO(ARG-GLY-ASP-D-PHE-VAL) Property

Density: 1.45±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: 1 N acetic acid: 5mg/mL
form: White solid
pka: 4.01±0.10(Predicted)
color: white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 182015
Product name: Cyclo(Arg-Gly-Asp-D-Phe-Val)
Purity: Potent inhibitor of cell adhesion.
Packaging: 1mg
Price: $238
Updated: 2025/07/31

Biosynth Carbosynth

Product number: FC108714
Product name: Cyclo(-Arg-Gly-Asp-D-Phe-Val) trifluoroacetate salt
Packaging: 1mg
Price: $131
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0004218
Product name: Cyclo(Arg-Gly-Asp-D-Phe-Val)
Purity: 95.00%
Packaging: 1MG
Price: $224.7
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC108714
Product name: Cyclo(-Arg-Gly-Asp-D-Phe-Val) trifluoroacetate salt
Packaging: 2mg
Price: $228
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC108714
Product name: Cyclo(-Arg-Gly-Asp-D-Phe-Val) trifluoroacetate salt
Packaging: 5mg
Price: $456
Updated: 2021/12/16

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CYCLO(ARG-GLY-ASP-D-PHE-VAL) Chemical Properties,Usage,Production

Uses

Cyclo(Arg-Gly-Asp-D-Phe-Val) (Cyclo(RGDfV)) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) can be used for the research of acute myeloid leukemia[1].

General Description

Potent inhibitor of cell adhesion. Inhibits tumor cell adhesion to laminin and vitronectin substrates. In vivo investigations in rats showed it to be useful in the amelioration of ischemic acute renal failure in rats. Also inhibits tubular obstruction by preventing cell-cell adhesion. Inhibits the redistribution of c-Src into focal adhesions, thereby leading to impaired MAP Kinase activation.

Biochem/physiol Actions

Primary Targetinhibits tumor cell adhesion to laminin and vitronectin substrates

References

[1] Shen ZH, et al. Targeting of the leukemia microenvironment by c(RGDfV) overcomes the resistance to chemotherapy in acute myeloid leukemia in biomimetic polystyrene scaffolds. Oncol Lett. 2016 Nov;12(5):3278-3284. DOI:10.3892/ol.2016.5042

CYCLO(ARG-GLY-ASP-D-PHE-VAL) Preparation Products And Raw materials

Raw materials

Preparation Products

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CYCLO(ARG-GLY-ASP-D-PHE-VAL) Suppliers

China 74 France 1 Japan 3 Switzerland 1 United Kingdom 2 United States 10 Global 91

Alabiochem Tech.Co., Ltd.

Tel: 512-58900862 400-0707518
Fax: 0086-512-56765862
Email: sales@alabiochem.com
Country: China
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GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
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Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
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Chemsky（shanghai）International Co.,Ltd.

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Email: shchemsky@sina.com
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Cellmano Biotech Limited

Tel: 0551-65326643 18156095617
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BOC Sciences

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Wuxi Zhongkun Biochemical Technology Co., Ltd.

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Hangzhou Peptide Biochem Co.,Ltd

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Alfa Chemistry

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Email: support@alfa-chemistry.com
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Creative Peptides

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ProdList: 6083
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View Lastest Price from CYCLO(ARG-GLY-ASP-D-PHE-VAL) manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: CYCLO(ARG-GLY-ASP-D-PHE-VAL) 137813-35-5
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-11

Career Henan Chemical Co

Product: CYCLO(ARG-GLY-ASP-D-PHE-VAL) 137813-35-5
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-13

137813-35-5, CYCLO(ARG-GLY-ASP-D-PHE-VAL)Related Search:

CYCLO(-GLY-ARG-GLY-ASP-SER-PRO-ALA) CYCLO[ASP(OBZ)-D-PHE-MEVAL-ARG(MTR)-GLY] CYCLO (ARG-GLY-ASP-D-PHE-VAL) ACOH 2H2O CYCLO(-ARG-ALA-ASP-D-PHE-VAL) CYCLO(ARG-GLY-ASP-D-PHE-VAL) Cilengitide

RGDFV PEPTIDE, CYCLIC

Cyclo(Arg-Gls-Asp-D-Phe-Val)

EMD 66203, c(RGDfV)

CYCLO(ARG-GLY-ASP-D-PHE-VAL)

CYCLO(RGDD-FV)

Cyclo(-Arg-Gly-Asp-D-Phe-Val) trifluoroacetate salt

Cyclo(Arg-Gly-Asp-D-Phe-Val) - CAS 137813-35-5 - Calbiochem

cRGDfV

EMD 66203

Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-valyl)

cyclo(RGD-DPhe-V)

137813-35-5

C26H38N8O7

Peptides

Other Peptides

Biochemicals and Reagents

Amino Acids and Peptides

BioChemical