Serine, N-[(1,1-dimethylethoxy)carbonyl]- (9CI)
- Product Name
- Serine, N-[(1,1-dimethylethoxy)carbonyl]- (9CI)
- CAS No.
- 3850-40-6
- Chemical Name
- Serine, N-[(1,1-dimethylethoxy)carbonyl]- (9CI)
- Synonyms
- N-BOC-Serine;Boc-DL-serine;(tert-Butoxycarbonyl)serine;(Tert-Butoxy)Carbonyl DL-Ser-OH;N-[(1,1-Dimethylethoxy)carbonyl]serine;Serine,N-[(1,1-diMethylethoxy)carbonyl]-;Serine, N-[(1,1-dimethylethoxy)carbonyl]- (9CI);3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid
- CBNumber
- CB81072758
- Molecular Formula
- C8H15NO5
- Formula Weight
- 205.21
- MOL File
- 3850-40-6.mol
Serine, N-[(1,1-dimethylethoxy)carbonyl]- (9CI) Property
- Boiling point:
- 385.1±37.0 °C(Predicted)
- Density
- 1.240±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 3.62±0.10(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- B810043
- Product name
- 2-((tert-Butoxycarbonyl)amino)-3-hydroxypropanoicAcid
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- AS47679
- Product name
- Boc-DL-serine
- Purity
- 95+%
- Packaging
- 1g
- Price
- $40
- Updated
- 2021/12/16
- Product number
- AS47679
- Product name
- Boc-DL-serine
- Purity
- 95+%
- Packaging
- 5G
- Price
- $132
- Updated
- 2021/12/16
- Product number
- CHM0092775
- Product name
- 2-TERT-BUTOXYCARBONYLAMINO-3-HYDROXY-PROPIONIC ACID
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $618.5
- Updated
- 2021/12/16
- Product number
- CHM0092775
- Product name
- 2-TERT-BUTOXYCARBONYLAMINO-3-HYDROXY-PROPIONIC ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $623.82
- Updated
- 2021/12/16
Serine, N-[(1,1-dimethylethoxy)carbonyl]- (9CI) Chemical Properties,Usage,Production
Synthesis
312-84-5
24424-99-5
3262-72-4
Sodium hydroxide (8.4 g, 0.110 mol) was dissolved in water (53 mL) and stirred at room temperature until completely dissolved, followed by cooling to 5-10 °C. D-serine (10.5 g, 0.100 mol) and di-tert-butyl dicarbonate (26.2 g, 0.120 mol) were slowly added while the temperature was maintained at ≤10 °C. The reaction mixture was gradually heated to 30-35 °C and the reaction was stirred at this temperature for 20 hours. Upon completion of the reaction, an aqueous solution of BOC-L-serine was obtained (yield based on 100%, HPLC purity 99.1%, chiral purity 99.4%). This aqueous solution can be used directly in the subsequent synthesis steps without further purification.
References
[1] Journal of the American Chemical Society, 1994, vol. 116, # 18, p. 8402 - 8403
[2] Journal of the American Chemical Society, 2008, vol. 130, # 7, p. 2351 - 2364
[3] Advanced Synthesis and Catalysis, 2016, vol. 358, # 1, p. 34 - 40
[4] Patent: CN104030943, 2016, B. Location in patent: Paragraph 0095; 0096
[5] Beilstein Journal of Organic Chemistry, 2014, vol. 10, p. 1114 - 1120
Serine, N-[(1,1-dimethylethoxy)carbonyl]- (9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
View Lastest Price from Serine, N-[(1,1-dimethylethoxy)carbonyl]- (9CI) manufacturers
- Product
- Serine, N-[(1,1-dimethylethoxy)carbonyl]- (9CI) 3850-40-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-13