5-Propargylamino-3'-azidomethyl-dUTP
- Product Name
- 5-Propargylamino-3'-azidomethyl-dUTP
- CAS No.
- 666847-57-0
- Chemical Name
- 5-Propargylamino-3'-azidomethyl-dUTP
- Synonyms
- 5-propargylamino-3' -N3-dUTP;5-Propargylamino-3'-Azidomethyl-dUTP;5-Propargylamino-3′-Azidomethyl-dUTP;5-Propargylamino-3'-azidomethyl-2'-deoxyuridine-5'-Triphosphate;3'-O-azidomethyl-5-(3-amino-prop-1-ynyl)-2'-deoxyuridine 5'-O-nucleoside triphosphate
- CBNumber
- CB810762198
- Molecular Formula
- C13H19N6O14P3
- Formula Weight
- 576.24
- MOL File
- 666847-57-0.mol
5-Propargylamino-3'-azidomethyl-dUTP Chemical Properties,Usage,Production
Description
5-Propargylamino-3'-azidomethyl-dUTP is a key building block for preparing fluorescent conjugates that are used in the next generation sequencing (NGS).
Uses
5-Propargylamino-3'-azidomethyl-dUTP is a nucleoside molecule extracted from patent WO2004018497A2, compound 5. 5-Propargylamino-3'-azidomethyl-dUTP can be used in DNA synthesis and DNA sequencing[1]. 5-Propargylamino-3'-azidomethyl-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
References
[1] Milton J, et, al. Modified nucleotides for polynucleotide sequencing. WO2004018497A2.
5-Propargylamino-3'-azidomethyl-dUTP Preparation Products And Raw materials
Raw materials
Preparation Products
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