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3H-imidazo[4,5-b]pyridine-2-carboxylic acid

Product Name
3H-imidazo[4,5-b]pyridine-2-carboxylic acid
CAS No.
97640-15-8
Chemical Name
3H-imidazo[4,5-b]pyridine-2-carboxylic acid
Synonyms
Pazopanib Impurity 113;2-imidazo[4,5-b]pyridinecarboxylic acid;1H-Imidazo[4,5-b]pyridine-2-carboxylic acid;3H-imidazo[4,5-b]pyridine-2-carboxylic acid
CBNumber
CB81080742
Molecular Formula
C7H5N3O2
Formula Weight
163.13
MOL File
97640-15-8.mol
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3H-imidazo[4,5-b]pyridine-2-carboxylic acid Property

storage temp. 
2-8°C
Appearance
White to light yellow Solid
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Safety

HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
I385958
Product name
3H-imidazo[4,5-b]pyridine-2-carboxylicacid
Packaging
5mg
Price
$60
Updated
2021/12/16
TRC
Product number
I385958
Product name
3H-imidazo[4,5-b]pyridine-2-carboxylicacid
Packaging
25mg
Price
$90
Updated
2021/12/16
Matrix Scientific
Product number
065644
Product name
3H-Imidazo[4,5-b]pyridine-2-carboxylic acid
Packaging
500mg
Price
$285
Updated
2021/12/16
Matrix Scientific
Product number
065644
Product name
3H-Imidazo[4,5-b]pyridine-2-carboxylic acid
Packaging
1g
Price
$357
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0322013
Product name
3H-IMIDAZO[4,5-B]PYRIDINE-2-CARBOXYLIC ACID
Purity
95.00%
Packaging
5MG
Price
$500.27
Updated
2021/12/16
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3H-imidazo[4,5-b]pyridine-2-carboxylic acid Chemical Properties,Usage,Production

Synthesis

24638-20-8

97640-15-8

Step 1004b: Preparation of 3H-imidazo[4,5-b]pyridine-2-carboxylic acid. To a boiling aqueous solution of KMnO4 (0.38 g, 2.4 mmol) (8 mL), an aqueous solution of 3H-imidazo[4,5-b]pyridine-2-methanol (0.20 g, 1.4 mmol) and Na2CO3 (0.19 g, 1.5 mmol) (6 mL) was slowly added. The reaction mixture was heated to reflux for 4 hours. The reaction mixture was filtered while hot and the filtrate was cooled to room temperature and the pH was adjusted with concentrated hydrochloric acid to 2. The precipitate precipitated was collected by vacuum filtration to afford 3H-imidazo[4,5-b]pyridine-2-carboxylic acid in 100% yield. Mass spectrometry (MS) analysis results: C7H5N3O2, m/z 164 (M + H)+.

References

[1] Patent: US2003/73707, 2003, A1

3H-imidazo[4,5-b]pyridine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3H-imidazo[4,5-b]pyridine-2-carboxylic acid Suppliers

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97640-15-8, 3H-imidazo[4,5-b]pyridine-2-carboxylic acidRelated Search:

ethyl 6-chloro-5-methyl-3H-imidazo[4,5-b]pyridine-2-carboxylate ethyl 5-methyl-3H-imidazo[4,5-b]pyridine-2-carboxylate 6-bromo-3H-imidazo[4,5-b]pyridine-2-carboxylic acid 3H-imidazo[4,5-b]pyridine-2-carboxylic acid ethyl 6-bromo-5-methyl-3H-imidazo[4,5-b]pyridine-2-carboxylate ethyl 3H-imidazo[4,5-b]pyridine-2-carboxylate 6-bromo-7-methyl-3H-imidazo[4,5-b]pyridine-2-carboxylic acid ethyl 6-fluoro-3H-imidazo[4,5-b]pyridine-2-carboxylate ethyl 6-bromo-7-methyl-3H-imidazo[4,5-b]pyridine-2-carboxylate 5-methyl-3H-imidazo[4,5-b]pyridine-2-carboxylic acid 5-chloro-3H-imidazo[4,5-b]pyridine-2-carboxylic acid 5-methoxy-3H-imidazo[4,5-b]pyridine-2-carboxylic acid ethyl 6-bromo-3H-imidazo[4,5-b]pyridine-2-carboxylate ethyl 5-methoxy-3H-imidazo[4,5-b]pyridine-2-carboxylate methyl 5-chloro-3H-imidazo[4,5-b]pyridine-2-carboxylate

  • 3H-imidazo[4,5-b]pyridine-2-carboxylic acid
  • 1H-Imidazo[4,5-b]pyridine-2-carboxylic acid
  • 2-imidazo[4,5-b]pyridinecarboxylic acid
  • Pazopanib Impurity 113
  • 97640-15-8