H-GLU-ASN-PRO-VAL-VAL-HIS-PHE-PHE-LYS-ASN-ILE-VAL-THR-PRO-ARG-THR-PRO-OH

Product Name: H-GLU-ASN-PRO-VAL-VAL-HIS-PHE-PHE-LYS-ASN-ILE-VAL-THR-PRO-ARG-THR-PRO-OH
CAS No.: 178823-45-5
Chemical Name: H-GLU-ASN-PRO-VAL-VAL-HIS-PHE-PHE-LYS-ASN-ILE-VAL-THR-PRO-ARG-THR-PRO-OH
Synonyms: MBP (83-99) (bovine);MYELIN BASIC PROTEIN (83-99) (BOVINE);8:PN:US20130183327 SEQID:9 claimed sequence;Myelin Basic Protein (83-99) (bovine) MBP (83-99) (bovine);H-GLU-ASN-PRO-VAL-VAL-HIS-PHE-PHE-LYS-ASN-ILE-VAL-THR-PRO-ARG-THR-PRO-OH;L-Proline, L-α-glutamyl-L-asparaginyl-L-prolyl-L-valyl-L-valyl-L-histidyl-L-phenylalanyl-L-phenylalanyl-L-lysyl-L-asparaginyl-L-isoleucyl-L-valyl-L-threonyl-L-prolyl-L-arginyl-L-threonyl-
CBNumber: CB8108157
Molecular Formula: C93H143N25O24
Formula Weight: 1995.28
MOL File: 178823-45-5.mol

More

Less

H-GLU-ASN-PRO-VAL-VAL-HIS-PHE-PHE-LYS-ASN-ILE-VAL-THR-PRO-ARG-THR-PRO-OH Property

Density: 1.46±0.1 g/cm3(Predicted)
storage temp.: -15°C
pka: 3.39±0.20(Predicted)
Sequence: H-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-OH

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

H-GLU-ASN-PRO-VAL-VAL-HIS-PHE-PHE-LYS-ASN-ILE-VAL-THR-PRO-ARG-THR-PRO-OH Chemical Properties,Usage,Production

Uses

MBP (83-99) is a MBP-specific T cell lines recognizing the immunodominant epitope. MBP (83-99) induces proliferation and IFN-γ secreting of T cells[1][2].

in vivo

MBP(83-99) (50 μg; subcutaneous injection; once) generates weak IFN-γ secreting T cells in immunize SJL/J mice^[2].

References

[1] Hemmer B, et al. Human T-cell response to myelin basic protein peptide (83-99): extensive heterogeneity in antigen recognition, function, and phenotype. Neurology. DOI:10.1212/wnl.49.4.1116
[2] Katsara M, et al. A double mutation of MBP(83-99) peptide induces IL-4 responses and antagonizes IFN-gamma responses. J Neuroimmunol. 2008 Aug 30;200(1-2):77-89. DOI:10.1016/j.jneuroim.2008.06.013

H-GLU-ASN-PRO-VAL-VAL-HIS-PHE-PHE-LYS-ASN-ILE-VAL-THR-PRO-ARG-THR-PRO-OH Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

H-GLU-ASN-PRO-VAL-VAL-HIS-PHE-PHE-LYS-ASN-ILE-VAL-THR-PRO-ARG-THR-PRO-OH Suppliers

China 38 United States 2 Global 40

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
Advantage: 58

Chem-Impex International, Inc.

Tel: --
Fax: --
Country: United States
ProdList: 6730
Advantage: 64

178823-45-5, H-GLU-ASN-PRO-VAL-VAL-HIS-PHE-PHE-LYS-ASN-ILE-VAL-THR-PRO-ARG-THR-PRO-OHRelated Search:

H-GLU-ASN-PRO-VAL-VAL-HIS-PHE-PHE-LYS-ASN-ILE-VAL-THR-PRO-ARG-THR-PRO-OH

Myelin Basic Protein (83-99) (bovine) MBP (83-99) (bovine)

MBP (83-99) (bovine)

MYELIN BASIC PROTEIN (83-99) (BOVINE)

8:PN:US20130183327 SEQID:9 claimed sequence

L-Proline, L-α-glutamyl-L-asparaginyl-L-prolyl-L-valyl-L-valyl-L-histidyl-L-phenylalanyl-L-phenylalanyl-L-lysyl-L-asparaginyl-L-isoleucyl-L-valyl-L-threonyl-L-prolyl-L-arginyl-L-threonyl-

178823-45-5