Elgodipine

Product Name: Elgodipine
CAS No.: 119413-55-7
Chemical Name: Elgodipine
Synonyms: Elgodipine;2,6-Dimethyl-4-(2,3-methylenebisoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-isopropyl 5-[2-[methyl(4-fluorobenzyl)amino]ethyl] ester;4-(1,3-Benzodioxol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3-[2-[[(4-fluorophenyl)methyl]methylamino]ethyl]5-isopropyl ester;3,5-Pyridinedicarboxylic acid, 4-(1,3-benzodioxol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3-[2-[[(4-fluorophenyl)methyl]methylamino]ethyl] 5-(1-methylethyl) ester
CBNumber: CB81118180
Molecular Formula: C29H33FN2O6
Formula Weight: 524.58
MOL File: 119413-55-7.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0007211
Product name: ELGODIPINE
Purity: 95.00%
Packaging: 5MG
Price: $502.6
Updated: 2021/12/16

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Elgodipine Chemical Properties,Usage,Production

Uses

Elgodipine (IQB-875 free base) is an orally active dihydropyridine calcium antagonist and an antianginal compound. Elgodipine inhibits both T- and L-type calcium channels (IC50: 32 and 2.3 nM). Elgodipine lowers systemic vascular resistance and improves systolic cardiac function[1][2][3].

IC 50

T-type calcium channel: 32 nM (IC₅₀); L-type calcium channel: 2.3 nM (IC₅₀)

References

[1] Kuhn A, et al. Hemodynamic and antiischemic effects of intravenous elgodipine, a new dihydropyridine calcium channel blocker, in patients with chronic stable angina. Cardiovasc Drugs Ther. 1995 Aug;9(4):595-600. DOI:10.1007/BF00878092
[2] Lepretre N, et al. Electrophysiological and radioligand binding studies of elgodipine and derivatives in portal vein myocytes. J Pharmacol Exp Ther. 1994 Dec;271(3):1209-15. PMID:7996428
[3] Acharya DU, et al. Anti-ischaemic and haemodynamic effects of elgodipine, a potent new generation calcium antagonist, in chronic stable angina. Eur Heart J. 1994 May;15(5):665-71. DOI:10.1093/oxfordjournals.eurheartj.a060565

Elgodipine Preparation Products And Raw materials

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Elgodipine Suppliers

China 7 United Kingdom 1 United States 3 Global 11

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29423
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49734
Advantage: 58

119413-55-7, ElgodipineRelated Search:

Diethyl2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate 3-(2-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER 2-(4-FLUOROBENZYLAMINO)ETHANOL 3-(2-METHOXYPHENYL)PROPIONIC ACID Elgodipine 3-(2-HYDROXY-PHENYL)-PROPIONIC ACID ETHYL ESTER AKOS BC-2739 3-(3-Methoxyphenyl)pentanedioic acid Oxodipine

2,6-Dimethyl-4-(2,3-methylenebisoxyphenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-isopropyl 5-[2-[methyl(4-fluorobenzyl)amino]ethyl] ester

4-(1,3-Benzodioxol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid 3-[2-[[(4-fluorophenyl)methyl]methylamino]ethyl]5-isopropyl ester

Elgodipine

3,5-Pyridinedicarboxylic acid, 4-(1,3-benzodioxol-4-yl)-1,4-dihydro-2,6-dimethyl-, 3-[2-[[(4-fluorophenyl)methyl]methylamino]ethyl] 5-(1-methylethyl) ester

119413-55-7

C29H33FN2O6