ChemicalBook > CAS DataBase List > (S)-3-Amino-3-(4-chlorophenyl)propan-1-ol

(S)-3-Amino-3-(4-chlorophenyl)propan-1-ol

Product Name
(S)-3-Amino-3-(4-chlorophenyl)propan-1-ol
CAS No.
886061-26-3
Chemical Name
(S)-3-Amino-3-(4-chlorophenyl)propan-1-ol
Synonyms
Ethanol,4-diazenyl-;Benzenepropanol,γ-amino-4-chloro-;(S)-3-(4-Chlorophenyl)-β-alaninol;(γS)-γ-Amino-4-chlorobenzenepropanol;(3S)-3-Amino-4-chlorobenzenepropanol;(S)-3-(4-CHLOROPHENYL)-BETA-ALANINOL;(S)-3-(4-Chlorophenyl)-β-Alaninol HCl;(S)-3-(4-chlorophenyl)-beta-alaninol HCl;Benzenepropanol, g-amino-4-chloro-, (gS);(S)-3-amino-2-(4-chlorophenyl)propan-1-ol
CBNumber
CB81118993
Molecular Formula
C9H12ClNO
Formula Weight
185.65
MOL File
886061-26-3.mol
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(S)-3-Amino-3-(4-chlorophenyl)propan-1-ol Property

Melting point:
53-56 °C
Boiling point:
327.9±27.0 °C(Predicted)
Density 
1.216
storage temp. 
2-8°C(protect from light)
pka
14.87±0.10(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1/C9H12ClNO/c10-8-3-1-7(2-4-8)9(11)5-6-12/h1-4,9,12H,5-6,11H2/t9-/s3
InChIKey
JGNACDMQJLVKIU-DJEYLCQNNA-N
SMILES
[C@H](C1C=CC(Cl)=CC=1)(N)CCO |&1:0,r|
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Safety

HS Code 
2922190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A595840
Product name
(S)-3-Amino-3-(4-chloro-phenyl)-propan-1-ol
Packaging
100mg
Price
$50
Updated
2021/12/16
TRC
Product number
A595840
Product name
(S)-3-Amino-3-(4-chloro-phenyl)-propan-1-ol
Packaging
250mg
Price
$100
Updated
2021/12/16
TRC
Product number
A595840
Product name
(S)-3-Amino-3-(4-chloro-phenyl)-propan-1-ol
Packaging
1g
Price
$210
Updated
2021/12/16
SynQuest Laboratories
Product number
4656-5-S1
Product name
(S)-3-Amino-3-(4-chlorophenyl)-1-propanol
Packaging
1g
Price
$216
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA30180
Product name
(S)-3-Amino-3-(4-chlorophenyl)-propan-1-ol
Packaging
2g
Price
$220
Updated
2021/12/16
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(S)-3-Amino-3-(4-chlorophenyl)propan-1-ol Chemical Properties,Usage,Production

Description

(S)-3-Amino-3-(4-chlorophenyl)propan-1-ol is an intermediate of capasitinib, which is used in the preparation of antitumour drugs.

Uses

(S)-3-amino-3-(4-chlorophenyl)propan-1-ol is commonly used as an intermediate in organic synthesis.

Synthesis

(S) -3-amino-3 -(4-chlorophenyl)propan-1-ol can be synthesized through chemical catalysis or biological transaminase catalysis.
(1) Chemical synthesis method: Using chloroacetonitrile and methanol as the starting substrates, HCl gas is introduced during the reaction process to obtain iminochloroethyl alkyl ether hydrochloride. Subsequently, Amino urea hydrochloride is added to obtain (S) -3-amino-3 -(4-chlorophenyl)propan-1-ol. Alternatively, (S) -3-amino-3 -(4-chlorophenyl) -propan-1-OL can be obtained through catalytic reduction using the prepared (S) -3-amino-3 -(4-chlorophenyl) -propionic acid as the precursor.
(2) Biosynthesis method: Using 1-(4-chlorophenyl) -3-hydroxyacetone as the substrate and transaminase (SEQ ID NO. 1-6) and its mutants as catalysts, (S) -3-amino-3 -(4-chlorophenyl)propan-1-ol is prepared through transamination reaction.

(S)-3-Amino-3-(4-chlorophenyl)propan-1-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-3-Amino-3-(4-chlorophenyl)propan-1-ol Suppliers

China 163 India 1 United Kingdom 2 United States 7 Global 173
Hangzhou Chemtrue Bio-Tech Co.,Ltd.
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0571-86828652 18857119830
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0571-83522824
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sales@chemtrue-bio.com
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China
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17653471880
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AstaTech (Chengdu) Pharma. Co., Ltd.
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15928766785 15928766785
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QQ961458712
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wupengcheng@astatech.cn
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China
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512-62857507
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sales@sinorarechem.com
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025-86950358 13390612682
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SICHUAN TONGSHENG BIOPHARMACEUTICAL CO., LTD
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0838-2809458 13350585791
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pharm@biots.cn
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China
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Shanghai Famo Bio-chemical Technology Company Ltd.
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021-02136680027 15800370750
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1706640024@qq.com
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China
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Shanghai Fengluan Biotechnology Co., LTD
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13357659136
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jing.z@fengluanbiotech.com
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China
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View Lastest Price from (S)-3-Amino-3-(4-chlorophenyl)propan-1-ol manufacturers

Jinan Ruitong Biotech Co., Ltd.
Product
(3S)-3-Amino-4-chlorobenzenepropanol 886061-26-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1
Release date
2025-08-28
Shaanxi Dideu New Materials Co. Ltd
Product
(S)-3-(4-CHLOROPHENYL)-BETA-ALANINOL 886061-26-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-03-19
Career Henan Chemical Co
Product
(S)-3-(4-CHLOROPHENYL)-BETA-ALANINOL 886061-26-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-25

886061-26-3, (S)-3-Amino-3-(4-chlorophenyl)propan-1-olRelated Search:

Fmoc-(S)-3-Amino-3-(4-chlorophenyl)propionic acid (S)-3-AMINO-3-(4-CHLORO-PHENYL)-PROPIONIC ACID Boc-(S)-3-Amino-3-(4-chlorophenyl)propionic acid (S)-3-Amino-3-(4-chlorophenyl)propan-1-ol (S)-3-AMINO-3-(2,4-DICHLORO-PHENYL)-PROPIONIC ACID (S)-7,8-DICHLORO-CHROMAN-4-YLAMINE METHYL (3S)-3-AMINO-3-(3,4-DICHLOROPHENYL)PROPANOATE (S)-3-AMINO-3-(4-CHLORO-PHENYL)-PROPIONIC ACID METHYL ESTER (S)-6,7-DICHLORO-CHROMAN-4-YLAMINE BOC-(S)-3-AMINO-3-(2,4-DICHLORO-PHENYL)-PROPIONIC ACID METHYL (3S)-3-AMINO-3-(4-CHLORO-2-FLUOROPHENYL)PROPANOATE FMOC-(S)-3-AMINO-3-(2,4-DICHLORO-PHENYL)-PROPIONIC ACID METHYL (3S)-3-AMINO-3-(2,4-DICHLOROPHENYL)PROPANOATE (S)-3-AMINO-3-(3,4-DICHLORO-PHENYL)-PROPIONIC ACID (S)-3-AMINO-3-(4-CHLORO-PHENYL)-PROPIONIC ACID ETHYL ESTER HCL cis-3,5-Bis(4-chlorophenyl)-3-((1H-imidazol-1-yl)-methyl)-2-methylisoxazolidine (S)-3-TERT-BUTOXYCARBONYLAMINO-3-(3,4-DICHLORO-PHENYL)-PROPIONIC ACID METHYL (3S)-3-AMINO-3-[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]PROPANOATE

  • (S)-3-(4-CHLOROPHENYL)-BETA-ALANINOL
  • (S)-3-(4-chlorophenyl)-beta-alaninol HCl
  • (S)-3-aMino-3-(4-chloro-phenyl)propan-1-ol&nbsp
  • (2S)-3-amino-2-(4-chlorophenyl)propan-1-ol
  • Benzenepropanol, .gamma.-amino-4-chloro-, (.gamma.S)-
  • Benzenepropanol, g-amino-4-chloro-, (gS)
  • (3S)-3-amino-3-(4-chlorophenyl)propan-1-ol
  • REF DUPL: (S)-beta-(4-chlorophenyl)alaninol
  • (S)-3-Amino-3-(4-chlorophenyl)-1-propanol
  • (S)-3-amino-2-(4-chlorophenyl)propan-1-ol
  • (S)-3-amino-3-(4-chlorophenyl)propan-1-ol886061-26-3
  • Benzenepropanol, γ-amino-4-chloro-, (γS)-
  • Ethanol,4-diazenyl-
  • (S)-3-(4-Chlorophenyl)-β-Alaninol HCl
  • (γS)-γ-Amino-4-chlorobenzenepropanol
  • (S)-3-(4-chlorophenyl)-beta-alaninol, CAS 886061-26-3
  • Benzenepropanol,γ-amino-4-chloro-
  • (S)-3-(4-Chlorophenyl)-β-alaninol
  • (3S)-3-Amino-4-chlorobenzenepropanol
  • (S)-3-Amino-3-(4-chloropheny!)propan-1-0l
  • 886061-26-3
  • 1