Pefurazoate
- Product Name
- Pefurazoate
- CAS No.
- 101903-30-4
- Chemical Name
- Pefurazoate
- Synonyms
- UR 0003;UHF 8615;Healthied;Pefurazoate Standard;4-pentenyl-N-furfuryl-N-imidazol-1-ylcarbonyl-DL-homoalaninate;pent-4-enyl 2-(2-furylmethyl-(imidazole-1-carbonyl)amino)butanoate;2-[Furfuryl(1H-imidazole-1-ylcarbonyl)amino]butanoic acid 4-pentenyl ester;pent-4-en-1-yl 2-{[(furan-2-yl)methyl](1H-imidazole-1-carbonyl)a mino}butanoate;2-[(2-Furanylmethyl)[(1H-imidazol-1-yl)carbonyl]amino]butanoic acid 4-pentenyl ester;Butanoic acid, 2-[(2-furanylmethyl)(1H-imidazol-1-ylcarbonyl)amino]-, 4-penten-1-yl ester
- CBNumber
- CB81120581
- Molecular Formula
- C18H23N3O4
- Formula Weight
- 345.39
- MOL File
- 101903-30-4.mol
Pefurazoate Property
- Melting point:
- 25°C
- Boiling point:
- 480.31°C (rough estimate)
- Density
- d420 1.152
- vapor pressure
- 0.648 x l0-4 Pa (23 °C)
- refractive index
- nD24.4 1.5140
- pka
- 3.8 (base)
- Water Solubility
- 443 mg l-1 (25 °C)
Safety
- Toxicity
- LD50 in male, female rats, male, female mice (mg/kg): 981, 1051, 1299, 946 orally; in rats (mg/kg): >2000 dermally; LC50 in rats (mg/m3): >3450 by inhalation; LC50 (48 hr) in carp, rainbow trout, bluegill sunfish (ppm): 16.9, 4.0, 12.0 (Takenaka, 1990)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H360May damage fertility or the unborn child
H371May cause damage to organs
H373May cause damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P309+P311IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P314Get medical advice/attention if you feel unwell.
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- AGR0000187
- Product name
- PEFURAZOATE
- Purity
- 95.00%
- Packaging
- 100ML
- Price
- $2629
- Updated
- 2021/12/16
Pefurazoate Chemical Properties,Usage,Production
Uses
Pefurazoate is used to control seed-borne fungal diseases, particularly Fusuriurn monuliniforme (Bakanae disease), Pyriculuriu ovyzae (rice blast) and Cuchliobolus rniyubeunus (brown spot) on rice plants. It also controls rice seedling blight caused by soil-borne pathogens (Trichoderme viride and Fusurium spp.) in nursery box cultivation, and other fungal pathogens on seeds of wheat, barley and flower bulbs.
Uses
Fungicide.
Definition
ChEBI: Pent-4-en-1-yl 2-[(2-furylmethyl)(imidazol-1-ylcarbonyl)amino]butanoate is a carboxylic ester obtained by formal condensation of the carboxy group of 2-[(2-furylmethyl)(imidazol-1-ylcarbonyl)amino]butanoic acid with the hydroxy group of pent-4-en-1-ol. It is a N-acylimidazole, a member of furans, a carboxylic ester and an olefinic compound.
Origin
This rice fungicide has been introduced by Showa Denko for the treatment of rice seedlings in Japan. It is based on a racemic homoalanine pentenyl ester backbone.
Safety Profile
Moderately toxic by ingestion, inhalation, and skin contact routes. Experimental reproductive effects.
Metabolic pathway
Pefurazoate is readily degraded in soils, plants and mammals and the molecule is susceptible to attack by enzymes at several sites. Metabolic cleavage of the molecule gives simpler fragments formed by loss of the imidazole ring.
Degradation
Pefurazoate is stable in acidic media and slightly unstable in alkaline media. It is stable to sunlight and decomposes only to the extent of about 1% after 90 days at 40 °C.
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