1-(4-BROMOPHENYL)PYRROLIDINE
- Product Name
- 1-(4-BROMOPHENYL)PYRROLIDINE
- CAS No.
- 22090-26-2
- Chemical Name
- 1-(4-BROMOPHENYL)PYRROLIDINE
- Synonyms
- N-(4-BROMOPHENYL)PYRROLIDINE;1-(4-BROMOPHENYL)PYRROLIDINE;1-Bromo-4-pyrrolidinobenzene;Pyrrolidine, 1-(4-broMophenyl)-;1-(4-Bromophenyl)pyrrolidine >1-(4-Bromophenyl)pyrrolidine 97+%
- CBNumber
- CB8113953
- Molecular Formula
- C10H12BrN
- Formula Weight
- 226.11
- MOL File
- 22090-26-2.mol
1-(4-BROMOPHENYL)PYRROLIDINE Property
- Melting point:
- 105.0 to 109.0 °C
- Boiling point:
- 306.1±25.0 °C(Predicted)
- Density
- 1.411±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 4.81±0.40(Predicted)
- color
- White to Almost white
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B3900
- Product name
- 1-(4-Bromophenyl)pyrrolidine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $38
- Updated
- 2025/07/31
- Product number
- B3900
- Product name
- 1-(4-Bromophenyl)pyrrolidine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $126
- Updated
- 2025/07/31
- Product number
- B700898
- Product name
- 1-(4-Bromophenyl)pyrrolidine
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 3H32-9-BU
- Product name
- 1-(4-Bromophenyl)pyrrolidine
- Packaging
- 1g
- Price
- $37
- Updated
- 2021/12/16
- Product number
- N539
- Product name
- N-(4-Bromophenyl)pyrrolidine
- Packaging
- 1g
- Price
- $85
- Updated
- 2021/12/16
1-(4-BROMOPHENYL)PYRROLIDINE Chemical Properties,Usage,Production
Synthesis
110-52-1
106-40-1
22090-26-2
Step 82a: Synthesis of 1-(4-bromophenyl)pyrrolidine (compound 0601-155) A mixture of 4-bromoaniline (1 g, 5.81 mmol), Cs2CO3 (5.68 g, 17.44 mmol), and 1,4-dibromobutane (1.88 g, 8.72 mmol) was dissolved in DMF (20 mL), and the reaction was stirred at 60 °C overnight. After completion of the reaction, the mixture was cooled to room temperature, diluted with water (200 mL) and extracted with ethyl acetate (2 x 100 mL). The organic layers were combined, washed sequentially with water (3 x 100 mL) and brine (100 mL) and dried over anhydrous Na2SO4. After concentration under reduced pressure, purified by silica gel column chromatography (eluent: petroleum ether), the target compound 0601-155 (720 mg, 46% yield) was obtained as a colorless oil.LCMS: 226 [M + 1]+.1H NMR (400MHz, DMSO-d6) δ1.94 (t, J=6.4Hz, 4H), 3.18 (t, J=6.4Hz, 4H), 6.18 (t, J=6.4Hz, 4H). Hz, 4H), 6.47 (d, J=9.2Hz, 2H), 7.27 (d, J=9.2Hz, 2H).
References
[1] Journal of the American Chemical Society, 2014, vol. 136, # 33, p. 11602 - 11605
[2] Journal of Organic Chemistry, 2006, vol. 71, # 1, p. 135 - 141
[3] Patent: WO2011/130628, 2011, A1. Location in patent: Page/Page column 221
[4] Patent: US2013/102595, 2013, A1. Location in patent: Paragraph 0550
[5] Patent: JP2015/187145, 2015, A. Location in patent: Paragraph 0468
1-(4-BROMOPHENYL)PYRROLIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
1-(4-BROMOPHENYL)PYRROLIDINE Suppliers
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- Country
- Belgium
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View Lastest Price from 1-(4-BROMOPHENYL)PYRROLIDINE manufacturers
- Product
- 1-(4-BROMOPHENYL)PYRROLIDINE 22090-26-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-30