ChemicalBook > CAS DataBase List > H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH

H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH

Product Name: H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH
CAS No.: 350228-37-4
Chemical Name: H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH
Synonyms: BACE-IN-1;P10-P4' StatVal;KTEEISEVN-STA-VAEF;KTEETSEVN(STAT)VAEF;B-SECRETASE INHIBITOR;KTEEISEVN [STATINE] VAEF;BETA-SECRETASE INHIBITOR;BETA-SECRETASE INHIBITOR 1;APP BETA-SECRETASE INHIBITOR;?-Secretase Inhibitor 1 - 1 mg
CBNumber: CB8114228
Molecular Formula: C73H118N16O27
Formula Weight: 1651.81
MOL File: 350228-37-4.mol

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H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH Property

Boiling point:: 1976.1±65.0 °C(Predicted)
Density: 1.317±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO: soluble
form: powder
pka: 3.48±0.10(Predicted)
color: white
Sequence: Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-{Sta}-Val-Ala-Glu-Phe

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FA109378
Product name: (Asn670, Sta 671,Val672)-Amyloid b/A4 Protein Precursor770 (662-675) ammonium salt
Packaging: 1mg
Price: $164
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA109378
Product name: (Asn670, Sta 671,Val672)-Amyloid b/A4 Protein Precursor770 (662-675) ammonium salt
Packaging: 2mg
Price: $285
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA109378
Product name: (Asn670, Sta 671,Val672)-Amyloid b/A4 Protein Precursor770 (662-675) ammonium salt
Packaging: 5mg
Price: $570
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0000802
Product name: AMYLOID PRECURSOR PROTEIN BETA-SECRETASE INHIBITOR
Purity: 95.00%
Packaging: 1MG
Price: $764.03
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA109378
Product name: (Asn670, Sta 671,Val672)-Amyloid b/A4 Protein Precursor770 (662-675) ammonium salt
Packaging: 10mg
Price: $991.3
Updated: 2021/12/16

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H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH Chemical Properties,Usage,Production

Uses

β-Secretase inhibitor ([Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)) is a β-secretase and BACE1 inhibitor (IC50: 25 nM for β-secretase)[1].

References

[1] Lin Liu, et al. A colorimetric strategy for assay of protease activity based on gold nanoparticle growth controlled by ascorbic acid and Cu(II)-coordinated peptide. Sensors and Actuators B: Chemical. Volume 266, 1 August 2018, Pages 246-254.
[2] Zhou Y, et al. Tyrosine-Conjugation Method for Evaluating BACE1 Activity Based on Silver Nanoparticles/Metal-Organic Framework Composites as Electrochemical Tags. Chemistry. 2023 May 16;29(28):e202300450. DOI:10.1002/chem.202300450

H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH Suppliers

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350228-37-4, H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OHRelated Search:

STATINE H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH

AMYLOID PRECURSOR PROTEIN BETA-SECRETASE INHIBITOR

A4 PROTEIN PRECURSOR770 (662-675)

BACE-IN-1

LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-[STATINE]-VAL-ALA-GLU-PHE

LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN(STATINE)-VAL-ALA-GLU-PHE-OH

LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN(STATIN)-VAL-ALA-GLU-PHE-OH

LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE

KTEETSEVN(STAT)VAEF

KTEEISEVN [STATINE] VAEF

KTEEISEVN-STA-VAEF

KTEEISEVN-Sta-VAEF(Sta=statine)

P10-P4' StatVal

L-Lysyl-L-threonyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-seryl-L-alpha-glutamyl-L-valyl-L-asparaginyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-L-valyl-L-alanyl-L-alpha-glutamyl-L-phenylalanine

(Asn670,Sta671,Val672)-AMyloid b/A4 Protein Precursor770 (662-675)

H-LYS-THR-GLU-GLU-ILE-SER-GLU-VAL-ASN-STA-VAL-ALA-GLU-PHE-OH

BETA-SECRETASE INHIBITOR

BETA-SECRETASE INHIBITOR 1

B-SECRETASE INHIBITOR

[ASN670, STA671, VAL672]AMYLOID-BETA

(ASN670,STA671,VAL672)-AMYLOID BETA/A4 PROTEIN PRECURSOR770 (662-675)

(ASN670,STA671,VAL672)-APP770 (662-675)

APP BETA-SECRETASE INHIBITOR

L-Phenylalanine, L-lysyl-L-threonyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-seryl-L-α-glutamyl-L-valyl-L-asparaginyl-(3S,4S)-4-amino-3-hydroxy-6-methylheptanoyl-L-valyl-L-alanyl-L-α-glutamyl-

(Asn670,Sta671,Val672)-Amyloid β/A4 Protein Precursor770 (662-675)

Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)

(Asn???,Sta??1,Val??2)-Amyloid β/A4 Protein Precursor??? (662-675) ammonium salt

(Asn???,Sta???,Val???)-Amyloid β/A4 Protein Precursor??? (662-675) ammonium salt

?-Secretase Inhibitor 1 - 1 mg

(Asn670, Sta671,Val672)-Amyloid b/A4 Protein Precursor770 (662-675) ammonium

(Asn670,Sta671,Va672)-Amyloid β/A4 Protein Precursor770 (662-675) ammonium salt

Lys-THR-E-Glu-I-S-E-Val-ASN-STA-Val-A-E-Phe

350228-37-4

C73H118N16O27

Enzyme Inhibitors by Enzyme

Enzyme Inhibitors

Enzymes, Inhibitors, and Substrates

R to Z

BioChemical

Biochemicals and Reagents

beta-Secretase

Pepetides

peptides

Amyloid beta-peptide and related

peptide

beta-SecretaseNeurobiology

β-SecretaseEnzyme Inhibitors by Enzyme

Alzheimers and Neurodegenerative Disease Research

Neurodegenerative Disease Peptides

Other Alzheimer Peptides

OtherNeuropeptides

Protease Inhibitor Specificity Index

Protease Inhibitors

R to