ChemicalBook > CAS DataBase List > MT-4
MT-4
- Product Name
- MT-4
- CAS No.
- 2327925-35-7
- Chemical Name
- MT-4
- Synonyms
- MT-4;MT-4 Cells Line;MT-4, 10 mM in DMSO;Benzeneacetamide, N-[4-[[4-(dimethylamino)-6-methyl-2-pyrimidinyl]amino]phenyl]-
- CBNumber
- CB81143674
- Molecular Formula
- C21H23N5O
- Formula Weight
- 361.44
- MOL File
- 2327925-35-7.mol
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MT-4 Property
- Density
- 1.246±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 14.54±0.70(Predicted)
- form
- Solid
- color
- Off-white to light yellow
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N-Bromosuccinimide Price
Biorbyt Ltd
- Product number
- orb527490
- Product name
- MT4
- Packaging
- 10μg
- Price
- $290.7
- Updated
- 2021/12/16
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MT-4 Chemical Properties,Usage,Production
Uses
MT-4 is a derivative of a tissue transglutaminase (TG2) inhibitor. MT-4 targets the complex of TG2 and fibronectin (FN) (TG2/FN) and inhibits the adhesion of tumor cells to the matrix. MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum and increases the sensitivity of OC cells to paclitaxel.
References
[1] Sima LE, et al. Small Molecules Target the Interaction between Tissue Transglutaminase and Fibronectin. Mol Cancer Ther. 2019 Jun;18(6):1057-1068. DOI:10.1158/1535-7163.MCT-18-1148
MT-4 Preparation Products And Raw materials
Raw materials
Preparation Products
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