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N-LAUROYL-D-ERYTHRO-SPHINGOSINE

Product Name
N-LAUROYL-D-ERYTHRO-SPHINGOSINE
CAS No.
74713-60-3
Chemical Name
N-LAUROYL-D-ERYTHRO-SPHINGOSINE
Synonyms
CERAMIDE C12;C12 CERAMIDE;12:0 CERAMIDE;N-Laurylsphingosine;N-lauroylsphingosine;N-LAUROYL-D-SPHINGOSINE;C12-D-ERYTHRO-SPHINGOSINE;C12 Ceramide (d18:1/12:0);N-Dodecanoyl-D-sphingosine;N-LAUROYL-D-ERYTHRO-SPHINGOSINE
CBNumber
CB8116181
Molecular Formula
C30H59NO3
Formula Weight
481.79
MOL File
74713-60-3.mol
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N-LAUROYL-D-ERYTHRO-SPHINGOSINE Property

Melting point:
70 - 72°C
Boiling point:
579.38°C (rough estimate)
Density 
0.9777 (rough estimate)
refractive index 
1.6310 (estimate)
storage temp. 
-20°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated)
pka
13.54±0.20(Predicted)
form 
Solid
color 
White to Off-White
BRN 
1717021
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Safety

Safety Statements 
24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
58199
Product name
N-Lauroyl-D-sphingosine
Purity
≥98.0% (TLC)
Packaging
50mg
Price
$410
Updated
2023/06/20
Sigma-Aldrich
Product number
58199
Product name
N-Lauroyl-D-sphingosine
Purity
≥98.0% (TLC)
Packaging
250mg
Price
$853
Updated
2023/06/20
Cayman Chemical
Product number
22530
Product name
C12 Ceramide (d18:1/12:0)
Purity
≥98%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
22530
Product name
C12 Ceramide (d18:1/12:0)
Purity
≥98%
Packaging
5mg
Price
$193
Updated
2024/03/01
Cayman Chemical
Product number
22530
Product name
C12 Ceramide (d18:1/12:0)
Purity
≥98%
Packaging
10mg
Price
$341
Updated
2024/03/01
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N-LAUROYL-D-ERYTHRO-SPHINGOSINE Chemical Properties,Usage,Production

Chemical Properties

white powder

Uses

C12 Ceramide (d18:1/12:0) or N-lauroyl-D-erythro-sphingosine has been used:

  • as a lipid standard in the optimization of the liquid chromatography-mass spectrometry (LC-MS) method conditions
  • as an internal standard for lipid extraction in U87MG (human glioma cell line)
  • as an internal standard for the quantification of ceramide using liquid chromatography-mass spectrometry (LC-MS) in rat tissues

Uses

Ceramide is one of the simplest sphingolipids, consisting of a sphingosine base N-linked to a fatty acid, and is a membrane mediator for cell-signaling events. N-Acyl chain length of membrane ceramides can influence bidimensional transitions, condensed domain morphology, and interfacial thickness.

Definition

ChEBI: N-dodecanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as dodecanoyl (lauroyl). It is functionally related to a dodecanoic acid.

General Description

Ceramide is a sphingolipid with long acyl chain attached to a fatty. It is synthesized in the endoplasmic reticulum by ceramide synthase.

Biochem/physiol Actions

Ceramides?are signaling sphingolipids, which are implicated in regulating stress responses and inflammation. It also regulates cell growth arrest, differentiation and apoptosis.

N-LAUROYL-D-ERYTHRO-SPHINGOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-LAUROYL-D-ERYTHRO-SPHINGOSINE Suppliers

Toronto Research Chemicals
Tel
--
Fax
--
Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
71
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View Lastest Price from N-LAUROYL-D-ERYTHRO-SPHINGOSINE manufacturers

Career Henan Chemical Co
Product
N-LAUROYL-D-ERYTHRO-SPHINGOSINE 74713-60-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
100kg
Release date
2020-03-11

74713-60-3, N-LAUROYL-D-ERYTHRO-SPHINGOSINERelated Search:


  • N-LAUROYL-D-ERYTHRO-SPHINGOSINE
  • N-LAUROYL-D-SPHINGOSINE
  • C12 CERAMIDE
  • C12-D-ERYTHRO-SPHINGOSINE
  • CERAMIDE C12
  • N-lauroylsphingosine
  • N-LAUROYL-D-ERYTHRO-SPHINGOSINE, 99+%, SYNTHETICAL
  • N-Lauroyl-D-erythro-sphingosineCeramide C12
  • [R-[R*,S*-(E)]]-N-[2-Hydroxy-1-(hydroxyMethyl)-3-heptadecenyl]dodecanaMide
  • N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxyMethyl)-3-heptadecen-1-yl]dodecanaMide
  • N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxyMethyl)-3-heptadecenyl]dodecanaMide
  • N-Laurylsphingosine
  • 12:0 CERAMIDE
  • n-lauroyl-d-erythro-sphingosinesynthetical
  • (2S,3R,4E)-2-(Lauroylamino)-4-octadecene-1,3-diol
  • C12 Ceramide (d18:1/12:0)
  • N-Dodecanoyl-D-sphingosine
  • N-LAUROYL-D-ERYTHRO-SPHINGOSINE;C12 CERAMIDE (D18:1/12:0)
  • Dodecanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-
  • N-Laurylsphingosine|||C12 Ceramide (d18:1/12:0)|||N-Lauroyl-D-erythro-sphingosine
  • 74713-60-3
  • Amines
  • Chiral Reagents
  • Intermediates & Fine Chemicals
  • Pharmaceuticals