ChemicalBook > CAS DataBase List > (2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE

(2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE

Product Name
(2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE
CAS No.
346440-54-8
Chemical Name
(2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE
Synonyms
(2S,5S)-5-Benzyl-2-(tert-butyl)-3-MethyliMidazolidin-4-one;MACMILLAN ORGANOCATALYST(TM) SS246;(2S 5S)-2-(1' 1'-DIMETHYLETHYL)-3-METHY&;(2S,5S)-2-TERT-BUTYL-3-METHYL-5-BENZYL-&;(2S,5S)-2-(1?,1?-dimethylethyl)-3-methyl-5-phe...;(2S,5S)-5-BENZYL-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE;(2S,5S)-2-T-BUTYL-3-METHYL-5-PHENYLMETHYL-4-IMIDAZOLIDINONE;(2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE;(2S,5S)-2-TERT-BUTYL-3-METHYL-5-PHENYLMETHYL-4-IMIDAZOLIDINONE;(2S,5S)-(-)-2-tert-Butyl-3-Methyl-5-benzyl-4-iMidazolidinone 97%
CBNumber
CB8117249
Molecular Formula
C15H22N2O
Formula Weight
246.35
MOL File
346440-54-8.mol
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(2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE Property

Melting point:
93-100 °C(lit.)
Boiling point:
378.0±35.0 °C(Predicted)
Density 
1.040±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to crystal
pka
5.59±0.60(Predicted)
color 
White to Light yellow
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
663107
Product name
(2S,5S)-(?)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone
Purity
97%
Packaging
1g
Price
$166.4
Updated
2024/03/01
Sigma-Aldrich
Product number
663107
Product name
(2S,5S)-(?)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone
Purity
97%
Packaging
500mg
Price
$242
Updated
2024/03/01
TCI Chemical
Product number
B4138
Product name
(2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone
Purity
>97.0%(GC)
Packaging
200mg
Price
$100
Updated
2024/03/01
TCI Chemical
Product number
B4138
Product name
(2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone
Purity
>97.0%(GC)
Packaging
1g
Price
$400
Updated
2024/03/01
TRC
Product number
B526628
Product name
(2s,5s)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone
Packaging
2.5mg
Price
$45
Updated
2021/12/16
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(2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE Chemical Properties,Usage,Production

Uses

(2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone is a second-generation MacMillan catalyst, which can be used as a chiral organocatalyst in:

  • The chiral transformation reaction, including Friedel-Crafts and Mukaiyama-Michael reactions.
  • The preparation of substituted spiroundecenetriones via asymmetric domino Knoevenagel/Diels-Alder reactions.
  • The asymmetric synthesis of β-hydroxy aldehydes and their dimethylacetals via aldehyde-aldehyde aldol condensation reaction.
  • The enantioselective α-fluorination of aldehydes using N-fluorobenzenesulfonamide as a fluorinating agent.
  • The stereoselective preparation of (oxomethyl)oxabicyclo[3.2.1]octenones and tricyclic pyrroles via [4+3] cycloaddition of (trialkylsiloxy)pentadienals to furans.

General Description

(2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone is a chiral imidazolidinone organocatalyst, developed by MacMillan and co-workers.

(2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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(2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE Suppliers

TCI (Shanghai) Development Co., Ltd.
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021-67121386
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China
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021-50460086-9 15921403865
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03-36680489
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03-3668-0520
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Japan
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+32 (0)37350701
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View Lastest Price from (2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE manufacturers

Henan Fengda Chemical Co., Ltd
Product
(2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE 346440-54-8
Price
US $34.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Henan Aochuang Chemical Co.,Ltd.
Product
(2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE 346440-54-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-18
Zhuozhou Wenxi import and Export Co., Ltd
Product
(2S,5S)-(-)-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone 97% 346440-54-8
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

346440-54-8, (2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONERelated Search:


  • MACMILLAN ORGANOCATALYST(TM) SS246
  • (2S,5S)-2-TERT-BUTYL-3-METHYL-5-BENZYL-&
  • (2S 5S)-2-(1' 1'-DIMETHYLETHYL)-3-METHY&
  • (2S,5S)-5-Benzyl-2-tert-butyl-3-methyl-4-imidazolidinone, (2S,5S)-2-tert-Butyl-3-methyl-5-phenylmethyl-4-imidazolidinone
  • (2S,5S)-()-2-tert-Butyl-3-methyl-5-benzyl-4-imidazolidinone,(2S,5S)-2-tert-Butyl-3-methyl-5-phenylmethyl-4-imidazolidinone, (2S,5S)-5-Benzyl-2-tert-butyl-3-methyl-4-imidazolidinone
  • (2S,5S)-5-Benzyl-2-(tert-butyl)-3-MethyliMidazolidin-4-one
  • (2S,5S)-(-)-2-tert-Butyl-3-Methyl-5-benzyl-4-iMidazolidinone 97%
  • (2<i>S</i>,5<i>S</i>)-(-)-2-<i>tert</i>-Butyl-3-methyl-5-benzyl-4-imidazolidinone
  • (2S,5S)-5-BENZYL-2-TERT-BUTYL-3-METHYL-4-IMIDAZOLIDINONE
  • (2S,5S)-2-T-BUTYL-3-METHYL-5-PHENYLMETHYL-4-IMIDAZOLIDINONE
  • (2S,5S)-(-)-2-TERT-BUTYL-3-METHYL-5-BENZYL-4-IMIDAZOLIDINONE
  • (2S,5S)-2-TERT-BUTYL-3-METHYL-5-PHENYLMETHYL-4-IMIDAZOLIDINONE
  • (2S,5S)-2-(1,1-dimethylethyl)-3-methyl-5-phenylmethyl-4-imidazolidinone
  • 4-Imidazolidinone, 2-(1,1-dimethylethyl)-3-methyl-5-(phenylmethyl)-, (2S,5S)-
  • (2S,5S)-2-(1?,1?-dimethylethyl)-3-methyl-5-phe...
  • 346440-54-8
  • Asymmetric Synthesis
  • Chiral Catalysts, Ligands, and Reagents