Ethyl2,6-PyridinedicarboxylateMono
- Product Name
- Ethyl2,6-PyridinedicarboxylateMono
- CAS No.
- 21855-16-3
- Chemical Name
- Ethyl2,6-PyridinedicarboxylateMono
- Synonyms
- 6-(Ethoxycarbonyl);Methyl dipicolinate;6-(Ethoxycarbonyl)picolinic acid;Ethyl2,6-PyridinedicarboxylateMono;6- (ethoxycarbonyl) pyridine formate;2,6-pyridinedicarboxylatemonoethylester;6-Ethoxycarbonyl-2-pyridinecarboxylic acid;2,6-Pyridinedicarboxylic acid, 2-ethyl ester;2,6-pyridinediCarbocylic acid monoethyl ester
- CBNumber
- CB81177020
- Molecular Formula
- C9H9NO4
- Formula Weight
- 195.17
- MOL File
- 21855-16-3.mol
Ethyl2,6-PyridinedicarboxylateMono Property
- Melting point:
- 116-117℃
- Boiling point:
- 396.2±27.0 °C(Predicted)
- Density
- 1.304±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 3.27±0.10(Predicted)
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- E895140
- Product name
- 6-(Ethoxycarbonyl)picolinicAcid
- Packaging
- 250mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- OR918772
- Product name
- 6-(Ethoxycarbonyl)pyridine-2-carboxylicacid
- Purity
- 95%
- Packaging
- 1g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- 1067AB
- Product name
- 6-(Ethoxycarbonyl)picolinicacid
- Packaging
- 10g
- Price
- $431
- Updated
- 2021/12/16
- Product number
- OR918772
- Product name
- 6-(Ethoxycarbonyl)pyridine-2-carboxylicacid
- Purity
- 95%
- Packaging
- 5g
- Price
- $445
- Updated
- 2021/12/16
- Product number
- 078706
- Product name
- 6-(Ethoxycarbonyl)pyridine-2-carboxylic acid
- Packaging
- 1g
- Price
- $489
- Updated
- 2021/12/16
Ethyl2,6-PyridinedicarboxylateMono Chemical Properties,Usage,Production
Synthesis
3739-94-4
64-17-5
15658-60-3
21855-16-3
The general synthetic procedure was as follows. 2,6-Pyridinedicarboxylic acid (1, 1.5 g, 8.98 mmol) was mixed with 24 mL of dichlorosulfoxide (SOCl2). The reaction mixture was heated to reflux for 3 hours. After completion of the reaction, excess dichlorosulfoxide was removed by distillation under reduced pressure. To the resulting white solid, 50 mL of tetrahydrofuran (THF) was added. After the solid was completely dissolved, ethanol (10.5 mmol) and N,N-diisopropylethylamine (DIEA, 10.5 mmol) were added slowly via syringe. The reaction mixture was heated to reflux for 4 hours. At the end of the reaction, the solvent was removed by distillation under reduced pressure. The residue was separated and purified by column chromatography to afford the target products diethyl 2,6-pyridinedicarboxylate and monoethyl 2,6-pyridinedicarboxylate.
References
[1] Tetrahedron, 2011, vol. 67, # 44, p. 8458 - 8464
Ethyl2,6-PyridinedicarboxylateMono Preparation Products And Raw materials
Raw materials
Preparation Products
Ethyl2,6-PyridinedicarboxylateMono Suppliers
- Tel
- 024-31298370 15040047923
- Fax
- 024-62665110
- yuanchengchem@163.com
- Country
- China
- ProdList
- 252
- Advantage
- 52
- Tel
- 021-20960837
- Fax
- 021-20960837
- market@aloespharm.com
- Country
- China
- ProdList
- 1302
- Advantage
- 55
- Tel
- 0512-56316828 4008675858
- Fax
- +86-512-56316826
- sales@amateksci.com
- Country
- China
- ProdList
- 9874
- Advantage
- 55
- Tel
- 025-57018978 18251899859
- Fax
- 025-57018008
- sales@chalf-pharm.com
- Country
- China
- ProdList
- 5674
- Advantage
- 50
- Tel
- 0371-53765687 18937137882
- Fax
- QQ:2885373884
- 2853979813@qq.com
- Country
- China
- ProdList
- 7992
- Advantage
- 55
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 400-711-5280 86-571-81025280
- Fax
- 86-571-85806285
- sales@molcore.com
- Country
- China
- ProdList
- 9967
- Advantage
- 58
- Tel
- 025-58859352 18068836627
- Fax
- 02557626880
- sales01@aikonchem.com
- Country
- China
- ProdList
- 15083
- Advantage
- 58
- Tel
- 15026866316
- 180642609@qq.com
- Country
- China
- ProdList
- 4967
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58