ChemicalBook > CAS DataBase List > Mepitiostane
Mepitiostane
- Product Name
- Mepitiostane
- CAS No.
- 21362-69-6
- Chemical Name
- Mepitiostane
- Synonyms
- 10364S;Mepitiostane;Mepitiostane (Contains ~15% 3α,4α-Epithio isomer);2a,3a-Epithio-17b-(cyclopentylmethoxy)-5a-androstane;2α,3α-Epithio-17β-(cyclopentylMethoxy)-5α-androstane;2α,3α-Epithio-17β-(1-Methoxycyclopentyloxy)-5α-androstane;2a,3a-Epithio-17b-(1-methoxycyclopentyloxy)-5a-androstane;2,3-Epithio-1H-cyclopenta[a]phenanthrene, androstane deriv.;2a,3a-Epithio-5a-androstan-17b-yl 1-methoxycyclopentyl ether;2α,3α-Epithio-5α-androstan-17β-yl 1-Methoxycyclopentyl Ether
- CBNumber
- CB81179125
- Molecular Formula
- C25H40O2S
- Formula Weight
- 404.65
- MOL File
- 21362-69-6.mol
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Mepitiostane Property
- Melting point:
- 98-101°
- alpha
- D20 +22.5 ±0.5° (c = 1 in chloroform)
- Boiling point:
- 496.21°C (rough estimate)
- Density
- 0.9998 (rough estimate)
- refractive index
- 1.5200 (estimate)
- solubility
- Chloroform (Slightly), Ethyl Acetate (Slightly)
- form
- Solid
- color
- White to Off-White
- Stability:
- Acid Sensitive
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- SHG0006892
- Product name
- MEPITIOSTANE
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $2425.5
- Updated
- 2021/12/16
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Mepitiostane Chemical Properties,Usage,Production
Originator
Thioderon,Shionogi,Japan,1979
Uses
An orally active anabolic and androgenic steroid. It is a steroidal anti-estrogen with anti-mammary tumor activity.
Definition
ChEBI: Mepitiostane is an organic molecular entity.
Manufacturing Process
A mixture of 1.759 g of 2α,3α-epithio-5α-androstan-17β-ol, 2.3 ml of 1- methoxycyclopentene, 20 mg of pyridine salt of p-toluenesulfonic acid and 20 ml of t-butanol is stirred for 4 hours at room temperature. The reaction mixture is poured into an aqueous solution of sodium carbonate and the whole extracted with dichloromethane. The extract is dried over anhydrous sodium sulfate and evaporated to remove solvent. Purification of the residue by chromatography over alumina gives 1.487 g of 17β-(1-methoxycyclopentyl) oxy-2α,3α-epithio-5α-androstane. Yield 68.2%. MP 98°C to 101°C.
Therapeutic Function
Antiestrogen
Mepitiostane Preparation Products And Raw materials
Raw materials
Preparation Products
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Mepitiostane Suppliers
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- Country
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21362-69-6, MepitiostaneRelated Search:
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Mepitiostane