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Tixocortol

Product Name
Tixocortol
CAS No.
61951-99-3
Chemical Name
Tixocortol
Synonyms
Cortisol 21-Thiol;11β,17-Dihydroxy-21-Mercaptoprogesterone;(11β)-11,17-Dihydroxy-21-Mercaptopregn-4-ene-3,20-dione;Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-mercapto-, (11β)-
CBNumber
CB81179943
Molecular Formula
C21H30O4S
Formula Weight
378.53
MOL File
61951-99-3.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
T447490
Product name
Tixocortol
Packaging
100mg
Price
$1455
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012677
Product name
TIXOCORTOL
Purity
95.00%
Packaging
500MG
Price
$1963.5
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
72683
Product name
Tixocortol
Packaging
50mg
Price
$650
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0012677
Product name
TIXOCORTOL
Purity
95.00%
Packaging
50MG
Price
$750.75
Updated
2021/12/16
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Tixocortol Chemical Properties,Usage,Production

Originator

Pivalone,Jouveinal,France,1978

Uses

Tixocortol is an anti-inflammatory agent. Tixocortol is used in fluorescent chemoaffinity labeling.

Definition

ChEBI: A steroid sulfide in which the sulfanyl group is at C-21 of a polyoxygenated derivative of pregn-4-ene.

Manufacturing Process

In a reactor of 50 liters, sodium S-thiopivalate is prepared from 100 g of S_x0002_thiopivalic acid (0.844 mol), 214 cc of solution of sodium methylate, 3.95 M (0.844 mol) in 25 liters of anhydrous acetone.
There are then added 285 g (0.603 mol) of dihydroxy-11β,17α-iodo-21-dioxo- 3,20-pregnene-4 and the mixture is brought up to the acetone reflux for two hours. The solvent is eliminated by distillation under vacuum until there is obtained a syrupy residue which is poured into 10 liters of iced water. The insoluble part is filtered and dried under vacuum.
The crude product is purified by recrystallization from ethanol; weight: 250 g; yield: 89.5%.

Therapeutic Function

Antiinflammatory

Tixocortol Preparation Products And Raw materials

Raw materials

Preparation Products

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Tixocortol Suppliers

61951-99-3, TixocortolRelated Search:


  • (11β)-11,17-Dihydroxy-21-Mercaptopregn-4-ene-3,20-dione
  • 11β,17-Dihydroxy-21-Mercaptoprogesterone
  • Cortisol 21-Thiol
  • Pregn-4-ene-3,20-dione, 11,17-dihydroxy-21-mercapto-, (11β)-
  • 61951-99-3
  • C21H30O4S
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids
  • Sulfur & Selenium Compounds