5-TRANS FLUPROSTENOL

Product Name: 5-TRANS FLUPROSTENOL
CAS No.: 57968-83-9
Chemical Name: 5-TRANS FLUPROSTENOL
Synonyms: 5-TRANS FLUPROSTENOL;WWSWYXNVCBLWNZ-BDFMIYKPSA-N;Travoprost Impurity 1（5- trans Fluprostenol）;9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17-18,19,20-TETRANOR-PROSTA-5E,13E-DIEN-1-OIC ACID;5-Heptenoic acid, 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-, [1R-[1α(E),2β(1E,3R*),3α,5α]]- (9CI)
CBNumber: CB8118105
Molecular Formula: C23H29F3O6
Formula Weight: 458.47
MOL File: Mol file

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5-TRANS FLUPROSTENOL Property

solubility: DMF: 100 mg/ml; DMSO: 100 mg/ml; Ethanol: 100 mg/ml; PBS (pH 7.2): 15 mg/ml

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16776
Product name: 5-trans Fluprostenol
Purity: ≥95%
Packaging: 1mg
Price: $87
Updated: 2024/03/01

Cayman Chemical

Product number: 16776
Product name: 5-trans Fluprostenol
Purity: ≥95%
Packaging: 5mg
Price: $384
Updated: 2024/03/01

Cayman Chemical

Product number: 16776
Product name: 5-trans Fluprostenol
Purity: ≥95%
Packaging: 10mg
Price: $680
Updated: 2024/03/01

AK Scientific

Product number: 1461AH
Product name: 5-TransFluprostenol
Packaging: 5mg
Price: $525
Updated: 2021/12/16

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5-TRANS FLUPROSTENOL Chemical Properties,Usage,Production

Description

Travoprost is the Alcon trade name for fluprostenol isopropyl ester, an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug.¹ Fluprostenol isopropyl ester is a prodrug which is converted by esterase enzymatic activity in the cornea to yield the corresponding free acid, fluprostenol.² 5-trans Fluprostenol is an impurity that is routinely found in bulk preparations of fluprostenol in amounts ranging from 1-3%. This impurity occurs in the finished prodrug Travoprost in similar amounts. The pharmacology of 5-trans fluprostenol has not been studied extensively to date.

References

1. Hellberg, M.R., Sallee, V.L., McLaughlin, M.A., et al. Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist J. Ocul. Pharmacol. Ther. 17(5),421-432(2001).
2. Sorbera, L.A., and Casta?er, J. Travoprost Drugs Future 25(1),41-45(2000).

5-TRANS FLUPROSTENOL Preparation Products And Raw materials

Raw materials

Preparation Products

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5-TRANS FLUPROSTENOL Suppliers

China 13 United States 2 Global 15

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2210
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6870
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
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Advantage: 58

Hangzhou Synstar pharmaceutical Technology CO.,Ltd

Tel: 0571-85361029
Fax: 0571-85361029
Email: synstar518@163.com
Country: China
ProdList: 1991
Advantage: 58

Guangzhou Dreampharm Biotechnology Co., Ltd.

Tel: 17825480238
Fax: QQ 3008233717
Email: 3008233717@qq.com
Country: China
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Standardpharm Co. Ltd.

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Email: overseasales1@yongstandards.com
Country: United States
ProdList: 14336
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Jinan blalong chemical co. LTD

Tel: 2710913286@.com
Email: 1513643261@qq.com
Country: China
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Guangzhou Juntang Technology Co., Ltd

Tel: 020-36607679 13502246435
Email: sales@dmstandards.com
Country: China
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Scinova Biotech(Guangzhou) Co., Ltd.

Tel: 13268215580
Email: scinova_sales@163.com
Country: China
ProdList: 7026
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57968-83-9, 5-TRANS FLUPROSTENOLRelated Search:

cis-Atovaquone 2-(4'-chloro-2,3,4,5-tetrahydro-[1,1'-biphenyl]-4-yl)-3-hydroxynaphthalene-1,4-dione O-Methyl Atovaquone 15(S)-Fluprostenol isopropyl ester 5,6-trans Travoprost Fluprostenol

9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17-18,19,20-TETRANOR-PROSTA-5E,13E-DIEN-1-OIC ACID

WWSWYXNVCBLWNZ-BDFMIYKPSA-N

Travoprost Impurity 1（5- trans Fluprostenol）

5-Heptenoic acid, 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-, [1R-[1α(E),2β(1E,3R*),3α,5α]]- (9CI)

5-TRANS FLUPROSTENOL

57968-83-9