2-naphthalen-1-ylpropan-2-ol

Product Name: 2-naphthalen-1-ylpropan-2-ol
CAS No.: 6301-54-8
Chemical Name: 2-naphthalen-1-ylpropan-2-ol
Synonyms: 2-naphthalen-1-ylpropan-2-ol;α,α-Dimethyl-1-naphthalenemethanol;α,α-Dimethylnaphthalene-1-methanol;α,α-Dimethyl-1-naphthalenemethanol;1-Naphthalenemethanol,a,a-dimethyl-;1-Naphthalenemethanol, α,α-dimethyl-;ALPHA,ALPHA-DIMETHYL-1-NAPHTHALENEMETHANOL
CBNumber: CB81256990
Molecular Formula: C13H14O
Formula Weight: 186.25
MOL File: 6301-54-8.mol

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2-naphthalen-1-ylpropan-2-ol Property

Melting point:: 80 °C(Solv: ligroine (8032-32-4))
Boiling point:: 130-140 °C(Press: 0.1 Torr)
Density: 1.087±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 14.36±0.29(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S374024
Product name: ALPHA,ALPHA-DIMETHYL-1-NAPHTHALENEMETHANOL
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $30.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: S374024
Product name: ALPHA,ALPHA-DIMETHYL-1-NAPHTHALENEMETHANOL
Purity: Aldrich
Packaging: 25mg
Price: $29.8
Updated: 2024/03/01

AK Scientific

Product number: 5887BA
Product name: 2-Naphthalen-1-ylpropan-2-ol
Packaging: 100mg
Price: $97
Updated: 2021/12/16

AK Scientific

Product number: 5887BA
Product name: 2-Naphthalen-1-ylpropan-2-ol
Packaging: 5g
Price: $486
Updated: 2021/12/16

Chemenu

Product number: CM231696
Product name: 2-(Naphthalen-1-yl)propan-2-ol
Purity: 95%
Packaging: 5g
Price: $701
Updated: 2021/12/16

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2-naphthalen-1-ylpropan-2-ol Chemical Properties,Usage,Production

Synthesis

90-11-9

67-64-1

6301-54-8

To a stirred solution of dry THF (400 mL) of 1-bromonaphthalene (12, 41.41 g, 0.2 mol) held at -78 °C under N2 atmosphere, a hexane solution (125 mL, 0.2 mol) of 1.6 M n-BuLi was slowly added dropwise via syringe. After the dropwise addition, the resulting solution was continued to be stirred at -78 °C for 1 hour. Subsequently, dry acetone (17.42 g, 0.3 mol) was added dropwise via syringe to the reaction system. The reaction mixture was stirred at -78 °C for 0.5 h. After that, it was brought to room temperature and stirring was continued for 1 h. The reaction mixture was then stirred at -78 °C for 0.5 h. The reaction mixture was slowly poured into ice water (2 L), stirred and extracted with CH2Cl2 (500 mL × 3). The organic phases were combined, washed with 5% brine (500 mL), dried over anhydrous Na2SO4 and concentrated under reduced pressure to give the crude product. The crude product was purified by column chromatography and then milled with n-hexane/EtOAc (1:100, v/v) to obtain the pure 2-(naphthalen-1-yl)-2-propanol (13) as colorless needle-like crystals (33.90 g, 91%). Melting point: 88.5-90°C (literature value: 83-85°C [18]).1H NMR (DMSO-d6, 400 MHz) δ: 8.84-8.87 (m, 1H), 7.87-7.90 (m, 1H), 7.78 (d, 1H, J = 8.0 Hz), 7.56 (dd, 1H, J = 0.8, 7.6 Hz), 7.43-7.49 (m, 2H), 7.40 (t, 1H, J = 7.8 Hz), 5.24 (s, 1H), 1.70 (s, 6H).

References

[1] Medicinal Chemistry, 2017, vol. 13, # 3, p. 260 - 281
[2] Journal of Organic Chemistry, 2014, vol. 79, # 17, p. 8348 - 8357
[3] Journal fuer Praktische Chemie (Leipzig), 1987, vol. 329, # 3, p. 439 - 446

2-naphthalen-1-ylpropan-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-naphthalen-1-ylpropan-2-ol Suppliers

China 24 India 1 United States 4 Global 29

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View Lastest Price from 2-naphthalen-1-ylpropan-2-ol manufacturers

Career Henan Chemical Co

Product: 2-naphthalen-1-ylpropan-2-ol 6301-54-8
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2020-01-08

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2-naphthalen-1-ylpropan-2-ol

α,α-Dimethyl-1-naphthalenemethanol

α,α-Dimethylnaphthalene-1-methanol

ALPHA,ALPHA-DIMETHYL-1-NAPHTHALENEMETHANOL

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1-Naphthalenemethanol, α,α-dimethyl-

α,α-Dimethyl-1-naphthalenemethanol

6301-54-8