4-Biphenylboronic acid

Product Name: 4-Biphenylboronic acid
CAS No.: 5122-94-1
Chemical Name: 4-Biphenylboronic acid
Synonyms: AKOS BRN-0030;4-Boronobiphenyl;RARECHEM AH PB 0261;4-Biphenylboric acid;4-Biphenylboronic ac;4-Biphenylboronicaci;4-Diphenyl Boric Acid;4-BIPHENYLBORONIC ACID;4-Diphenylboronic acid;BIPHENYL-4-BORONIC ACID
CBNumber: CB8127772
Molecular Formula: C12H11BO2
Formula Weight: 198.03
MOL File: 5122-94-1.mol

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4-Biphenylboronic acid Property

Melting point:: 232-245 °C (lit.)
Boiling point:: 385.5±35.0 °C(Predicted)
Density: 1.18±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Acetone,Methanol
pka: 8.61±0.10(Predicted)
form: Powder
color: White
Water Solubility: Insoluble in water.
BRN: 2937410
InChI: InChI=1S/C12H11BO2/c14-13(15)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9,14-15H
InChIKey: XPEIJWZLPWNNOK-UHFFFAOYSA-N
SMILES: B(C1=CC=C(C2=CC=CC=C2)C=C1)(O)O
CAS DataBase Reference: 5122-94-1(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20/21/22
Safety Statements: 26-37/39-36-24/25
WGK Germany: 3
TSCA: No
HazardClass: IRRITANT
HS Code: 29310095

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 483451
Product name: 4-Biphenylboronic acid
Purity: ≥95.0%
Packaging: 5g
Price: $22.24
Updated: 2025/07/31

Sigma-Aldrich

Product number: 483451
Product name: 4-Biphenylboronic acid
Purity: ≥95.0%
Packaging: 25g
Price: $107
Updated: 2025/07/31

TCI Chemical

Product number: B2294
Product name: 4-Biphenylboronic Acid (contains varying amounts of Anhydride)
Packaging: 5g
Price: $28
Updated: 2025/07/31

TCI Chemical

Product number: B2294
Product name: 4-Biphenylboronic Acid (contains varying amounts of Anhydride)
Packaging: 25g
Price: $86
Updated: 2025/07/31

TRC

Product number: B535233
Product name: 4-Biphenylboronic acid
Packaging: 1g
Price: $55
Updated: 2021/12/16

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4-Biphenylboronic acid Chemical Properties,Usage,Production

Chemical Properties

Solid

Uses

suzuki reaction: Suzuki coupling of 2-(4-bromophenyl)thiophene with phenylboronic acid and 4-biphenylboronic acid are used for the preparation of 4-(2-thieny)biphenyl and 4-(2-thienyl)-1,1':4,1''-biphenyl respectively. Coupling of two equivalents of 4-(2-thienyl)phenylboronic acid with 1,4-diiodobenzene gives 4,4''-bis(2-thienyl)-1,1':4,1''-terphenyl and with 2,5-diiodothiophene, 2,5-bis[4-(2-thienyl)-phenyl]-thiophene is obtained.

Uses

Used in Suzuki reactions and as intermediates of liquid crystals.

Synthesis

92-66-0

5122-94-1

The general procedure for the synthesis of 4-biphenylboronic acid from 4-bromobiphenyl was as follows: 4-bromobiphenyl (30 g, 0.12 mol) was added to a single-neck flask and the reaction was carried out under argon protection. Tetrahydrofuran (THF) (500 mL) was added and stirred at -78 °C for 10 min. Slowly n-butyllithium (2.5 M in hexane) (77 mL, 0.19 mol) was added and the mixture was stirred at -78 °C for 1 hour. Subsequently, dimethyl borate (21.9 mL, 0.19 mol) was added at -78 °C and stirring was continued at -78 °C for 30 min, then brought to room temperature and stirred for 4 hours. After completion of the reaction, extraction was carried out with distilled water and ethyl acetate (EA) and the organic layer was dried with anhydrous magnesium sulfate (MgSO4). The solvent was removed using a rotary evaporator. Finally, pure 4-biphenylboronic acid (21 g, 84% yield) was isolated by column chromatography using hexane and ethyl acetate (EA) as eluents.

References

[1] Patent: WO2011/105700, 2011, A1. Location in patent: Page/Page column 18; 19; 21; 22
[2] Angewandte Chemie - International Edition, 2006, vol. 45, # 9, p. 1404 - 1408
[3] Tetrahedron, 2007, vol. 63, # 20, p. 4297 - 4303
[4] Journal of Organic Chemistry, 2011, vol. 76, # 4, p. 1013 - 1030
[5] Journal of the Chemical Society [Section] C: Organic, 1966, p. 566 - 571

4-Biphenylboronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Biphenylboronic acid Suppliers

Americas 1 Belgium 3 Canada 1 China 321 Europe 4 France 4 Germany 12 India 16 Italy 1 Japan 4 Jordan 1 Lithuania 1 Russia 1 South Korea 1 Switzerland 2 United Kingdom 23 United States 59 Global 455

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View Lastest Price from 4-Biphenylboronic acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4-Biphenylboronic acid 5122-94-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-04-07

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 4-Biphenylboronic acid 5122-94-1
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-03

Henan Aochuang Chemical Co.,Ltd.

Product: 4-Biphenylboronic acid 5122-94-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-27

5122-94-1, 4-Biphenylboronic acidRelated Search:

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RARECHEM AH PB 0261

(1,1'-BIPHENYL-4-YL)BORONIC ACID

AKOS BRN-0030

4-PHENYLBENZENEBORONIC ACID

4-PHENYLPHENYLBORONIC ACID

4-BIPHENYLBORONIC ACID

4-BIPHENYLYLBORONIC ACID

BIPHENYL-4-BORONIC ACID

4-Biphenylboric acid

4-Biphenylboronic acid, 98+%

4-Diphenyl Boric Acid

Biphenyl-4-boronic acid 98%

4-Biphenylboronic Acid (contains varying amounts of Anhydride)

Biphenyl-4-boronic acid, 98+%

4-Biphenylboronic ac

4-Biphenylboronic Acid&nbsp

Biphenyl-4-ylboronic acid

(1,1'-Biphenyl)-4-boronic acid

4-Biphenylboronic acid >=95.0%

4-Biphenylboronic acid [1,1'-Biphenyl]-4-ylboronic acid

[1,1'-Diphenyl]-4-ylboronic acid

4-Diphenylboronic acid

BORONICACID, B-[1,1'-BIPHENYL]-4-YL-

4-Boronobiphenyl

4-Biphenylboronic Acid (contains varying amounts of ahydride)

4-Biphenylboronicaci

B-[1,1'-biphenyl]-4-yl-Boronic acid

5122-94-1 4-Biphenylboronic acid

4-Biphenylboronic acid (6CI, 7CI, 8CI)

4Biphenylboronic acid,4 Biphenylboronic acid

1,1'-Biphenyl-4-ylboronic acid

Boronic acid, B-[1,1'-biphenyl]-4-yl-

1,1'-biphenyl]-4-ylboronic acid 98%min

5122-94-1

C12H11BO2

BORONIC ACID

B (Classes of Boron Compounds)

Boronic Acids

Boronic acid

Organoborons

Aryl

Boronic Acids

Boronic Acids and Derivatives

B (Classes of Boron Compounds)

Boronic Acids

Boronic acid series

Substituted Boronic Acids

blocks

BoronicAcids

Boron Compounds