Physical Form
ChemicalBook > CAS DataBase List > 3-BROMO-2-PHENYLPYRIDINE

3-BROMO-2-PHENYLPYRIDINE

Physical Form
Product Name
3-BROMO-2-PHENYLPYRIDINE
CAS No.
91182-50-2
Chemical Name
3-BROMO-2-PHENYLPYRIDINE
Synonyms
3-BROMO-2-PHENYLPYRIDINE;Pyridine, 3-bromo-2-phenyl-;1,1'-Biphenyl, 2,2',6,6'-tetrakis(chloromethyl)-
CBNumber
CB8131061
Molecular Formula
C11H8BrN
Formula Weight
234.09
MOL File
91182-50-2.mol
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3-BROMO-2-PHENYLPYRIDINE Property

Boiling point:
296.1±20.0 °C(Predicted)
Density 
1.426±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
2.08±0.10(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C11H8BrN/c12-10-7-4-8-13-11(10)9-5-2-1-3-6-9/h1-8H
InChIKey
QODMOFYNGFSWSQ-UHFFFAOYSA-N
SMILES
C1(C2=CC=CC=C2)=NC=CC=C1Br
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B698568
Product name
3-Bromo-2-phenylpyridine
Packaging
50mg
Price
$55
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB140797
Product name
3-Bromo-2-phenylpyridine
Packaging
100mg
Price
$66
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB140797
Product name
3-Bromo-2-phenylpyridine
Packaging
500mg
Price
$230
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0012255
Product name
3-BROMO-2-PHENYLPYRIDINE
Purity
95.00%
Packaging
250MG
Price
$315
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB140797
Product name
3-Bromo-2-phenylpyridine
Packaging
250mg
Price
$132.5
Updated
2021/12/16
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3-BROMO-2-PHENYLPYRIDINE Chemical Properties,Usage,Production

Physical Form

Solid

Chemical Properties

3-Bromo-2-phenylpyridine is stable under recommended storage conditions.

Uses

3-BROMO-2-PHENYLPYRIDINE is a useful research chemical.

Hazard

3-Bromo-2-phenylpyridine is acute toxicity, can cause skin corrosion/irritation.

Synthesis

13534-89-9

98-80-6

91182-50-2

General procedure for the synthesis of 3-bromo-2-phenylpyridine from 2,3-dibromopyridine and phenylboronic acid: a screw-capped vial was charged with a solvent mixture of acetonitrile (MeCN) and methanol (MeOH) (2:1, 15 mL), 2,3-dibromopyridine (474 mg, 2.0 mmol), phenylboronic acid (2.1 mmol), potassium carbonate (K2CO3, 560 mg, 4.0 mmol), triphenylphosphine (PPh3, 52 mg, 10 mol%) and palladium acetate (Pd(OAc)). 4.0 mmol), triphenylphosphine (PPh3, 52 mg, 10 mol%) and palladium acetate (Pd(OAc)2, 23 mg, 5 mol%). The reaction mixture was displaced three times with argon to remove oxygen, sealed and placed in a 50°C oil bath with stirring for 24 hours. Upon completion of the reaction, the mixture was cooled to room temperature and filtered through a diatomaceous earth pad to remove solid impurities. The filtrate was concentrated under reduced pressure and the resulting residue was dissolved in dichloromethane (CH2Cl2, 20 mL) and subsequently washed with water (3 x 10 mL) and the organic phase was dried over anhydrous sodium sulfate (Na2SO4). The solvent was removed by evaporation under reduced pressure and the residue was purified by silica gel column chromatography with the eluent being petroleum ether-ethyl acetate (30:1) to afford pure 3-bromo-2-phenylpyridine (2a) in the yield of 387 mg (83%) as a colorless oil.

References

[1] Tetrahedron, 2013, vol. 69, # 51, p. 10996 - 11003
[2] Chemistry of Heterocyclic Compounds, 2017, vol. 53, # 10, p. 1103 - 1113
[3] Khim. Geterotsikl. Soedin., 2017, vol. 53, # 10, p. 1103 - 1113,11
[4] Synlett, 2009, # 7, p. 1081 - 1086

3-BROMO-2-PHENYLPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BROMO-2-PHENYLPYRIDINE Suppliers

Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
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61
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
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sales@chemreagents.com
Country
United States
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10186
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62
Tetranov Biopharm
Tel
13526569071
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sales@leadmedpharm.com
Country
China
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7892
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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
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025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
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China
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9ding chemical ( Shanghai) Limited
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4009209199
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86-021-52271987
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sales@9dingchem.com
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China
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Synchem OHG
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+49 5662 408730
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+49 5662 4087320
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info@synchem.de
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Germany
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ShangHai AmK Pharmaceutical Technology Co., Ltd.
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微信 17321281695 18019252918
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sale@amkchem.com
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China
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Cool Pharm, Ltd
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021-60455363 18019463053
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50966098
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China
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Shanghai Chenzhu Pharmaceutical Co., Ltd.
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13162380607
Fax
QQ:1696175688
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China
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Guanmat Optoelectronic Materials (Jiangxi) Inc.
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0799-3607521 17379923216
Fax
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China
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View Lastest Price from 3-BROMO-2-PHENYLPYRIDINE manufacturers

Henan Fengda Chemical Co., Ltd
Product
3-Bromo-2-phenylpyridine 91182-50-2
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-31
Beijing Yanhua Jilian Opto-Electronic Technology Co., Ltd.
Product
3-BROMO-2-PHENYLPYRIDINE 91182-50-2
Price
US $0.00/ASSAYS
Min. Order
10ASSAYS
Purity
99.9%
Supply Ability
20
Release date
2019-08-05