Win 54954

Product Name: Win 54954
CAS No.: 107355-45-3
Chemical Name: Win 54954
Synonyms: Win 54954;5-{5-[2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy]pentyl}-3-methylisoxazole;5-[5-[2,6-Dichloro-4-[(4,5-dihydrooxazol)-2-yl]phenoxy]pentyl]-3-methylisoxazole;Isoxazole, 5-[5-[2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy]pentyl]-3-methyl-
CBNumber: CB81323131
Molecular Formula: C18H20Cl2N2O3
Formula Weight: 383.27
MOL File: 107355-45-3.mol

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Win 54954 Property

Boiling point:: 555.4±50.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted)
storage temp.: 4°C, protect from light
solubility: DMSO : 100 mg/mL (260.91 mM; Need ultrasonic)
form: Solid
pka: 3.77±0.50(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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Win 54954 Chemical Properties,Usage,Production

Uses

WIN 54954 is an orally active and broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections[1][2].

Definition

ChEBI: WIN54954 is an aromatic ether.

in vivo

WIN 54954 (2-100 mg/kg; p.o.) protects 50% of the mice from developing paralysis following infection with coxsackievirus A-9 and echovirus-9 at the dose of 2 and 100 mg/kg, respectively^[1].

References

[1] Woods MG, et, al. In vitro and in vivo activities of WIN 54954, a new broad-spectrum antipicornavirus drug. Antimicrob Agents Chemother. 1989 Dec;33(12):2069-74. DOI:10.1128/AAC.33.12.2069
[2] Fechner H, et, al. Pharmacological and biological antiviral therapeutics for cardiac coxsackievirus infections. Molecules. 2011 Oct 11;16(10):8475-503. DOI:10.3390/molecules16108475

Win 54954 Preparation Products And Raw materials

Raw materials

Preparation Products

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Win 54954 Suppliers

China 6 Global 6

WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.

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107355-45-3, Win 54954Related Search:

Win 54954

5-[5-[2,6-Dichloro-4-[(4,5-dihydrooxazol)-2-yl]phenoxy]pentyl]-3-methylisoxazole

5-{5-[2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy]pentyl}-3-methylisoxazole

Isoxazole, 5-[5-[2,6-dichloro-4-(4,5-dihydro-2-oxazolyl)phenoxy]pentyl]-3-methyl-

107355-45-3