forphenicinol

Product Name: forphenicinol
CAS No.: 71522-58-2
Chemical Name: forphenicinol
Synonyms: BF121;BF-121;BF 121;forphenicinol;α-Amino-3-hydroxy-4-(hydroxymethyl)benzeneacetic acid;Benzeneacetic acid, α-amino-3-hydroxy-4-(hydroxymethyl)-, (αS)-
CBNumber: CB81326415
Molecular Formula: C9H11NO4
Formula Weight: 197.189
MOL File: 71522-58-2.mol

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forphenicinol Property

Boiling point:: 334.28°C (rough estimate)
Density: 1.3075 (rough estimate)
refractive index: 1.5270 (estimate)
storage temp.: -20°C
solubility: DMSO: soluble,Methanol: soluble,
form: A solid
Water Solubility: Water: soluble

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Hazard and Precautionary Statements (GHS)

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forphenicinol Chemical Properties,Usage,Production

Uses

Forphenicinol is an immunomodulator and a derivative of the bacterial metabolite forphenicine. It increases the phagocytosis of yeast by peritoneal macrophages isolated from thioglycolate-stimulated mice. Forphenicinol (100 μg/animal) prevents cyclophosphamide-induced suppression of delayed-type hypersensitivity (DTH), as well as enhances DTH in response to the hapten oxazolone or sheep red blood cells in mice. It enhances the bactericidal activity of macrophages against P. aeruginosa in mice when administered at a dose of 0.5 mg/kg.2 Forphenicinol (15.6-1,000 μg/animal) increases survival in a mouse model of P. aeruginosa infection. It also inhibits tumor growth in S180 sarcoma and IMC carcinoma mouse xenograft models when administered at doses ranging from 0.05 to 5 mg/kg per day.

References

[1] Ishizuka, et al. Studies on effects of forphenicinol on immune responses. J. Antibiot. (Tokyo) 35(8), 1042-1048 (1982).

forphenicinol Preparation Products And Raw materials

Raw materials

Preparation Products

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forphenicinol Suppliers

China 7 United States 3 Global 10

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Binhai gill polypeptide co. LTD

Tel: 021-61263389 13524856427
Fax: WeChat630417570
Email: Joetang@glschina.com
Country: China
ProdList: 10000
Advantage: 58

Shanghai Anhua Biotechnology Co., Ltd.

Tel: 021-61263375 18168859245
Country: China
ProdList: 5958
Advantage: 58

Wuxi maimo topp biotechnology co., LTD

Tel: 13771048682 15061806929
Email: alice@mimotopes.cn
Country: China
ProdList: 5796
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 11973
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39035
Advantage: 58

71522-58-2, forphenicinolRelated Search:

(S)-3-HYDROXYPHENYLGLYCINE (RS)-3-HYDROXYPHENYLGLYCINE (S)-4-CARBOXY-3-HYDROXYPHENYLGLYCINE 2-AMINO-2-(4-METHYLPHENYL)ACETIC ACID Benzenemethanol, 4-[(1R)-1-aminoethyl]- forphenicinol

forphenicinol

α-Amino-3-hydroxy-4-(hydroxymethyl)benzeneacetic acid

Benzeneacetic acid, α-amino-3-hydroxy-4-(hydroxymethyl)-, (αS)-

BF 121

BF121

BF-121

71522-58-2