ChemicalBook > CAS DataBase List > TOTO 1
TOTO 1
- Product Name
- TOTO 1
- CAS No.
- 143413-84-7
- Chemical Name
- TOTO 1
- Synonyms
- DiTO?-1;Chebi:52298;Toto 1 Iodide;Thiazole Orange Dimer;DiTO-1 (equivalent to TOTO-1) *5 mM DMSO Solution* *CAS 143413-84-7*;1,1'-(4,4,7,7-tetramethyl-4,7-diazaundecamethylene)bis-4-(3-methyl-2,3-dihydro(benzo-1,3-thiazole)-2-methylidene)quinolinium;1,1'-(4,4,7,7-Tetramethyl-4,7-diazaundecamethylene)-bis-4-(3-methyl-2,3-dihydro-(benzo-1,3-thiazole)-2-methylidene)-quinolinium tetraiodide;1,1'-{Propane-1,3-diylbis[(dimethylammonio)propane-3,1-diyl]}bis{4-[(3-methyl-1,3-benzothiazol-2(3H)-ylidene)methyl]quinolinium} tetraiodide;Quinolinium, 1,1 0 -[1,3-propanediylbis [(dimethyliminio)-3,1-propanediyl]]bis[4-[(3-methyl-2 (3h)-benzothiazolylidene)methyl]-, Tetraiodide;2,2'-{Propane-1,3-diylbis[(dimethylammonio)propane-3,1-diylquinolin-1-yl-4-ylidenemethylylidene]}bis(3-methyl-1,3-benzothiazol-3-ium) tetraiodide
- CBNumber
- CB81336094
- Molecular Formula
- C49H58I4N6S2
- Formula Weight
- 1302.7729
- MOL File
- 143413-84-7.mol
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TOTO 1 Property
- Melting point:
- >250 ℃
- solubility
- Soluble in dimethyl sulfoxide
- form
- powder
- color
- Red
- Appearance
- orange solution
- λmax
- 514 nm
- ex/em
- 514/533 nm
- ε(extinction coefficient)
- 117000 cm−1M−1
- Φ(quantum yield)
- 0.34
- Biological Applications
- Nucleic acid hybridization; nucleic acid amplification assay; DNA fragment sizing; detecting nucleic acids,cells,cystic fibrosis mutations,genes,human papilloma virus (HPV),intact recombinant viruses,oncoprotein
- Major Application
- Marker systems for product authentication
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TOTO 1 Chemical Properties,Usage,Production
Description
TODi-1 (Thiazole Orange Homodimer, also known as TOTO®-1) is a green fluorescent carbocyanine dimeric dye. TODi-1 is a cell-impermeant nucleic acid stain that is nonfluorescent in the absence of nucleic acids but exhibits a multiple fluorescence enhancement upon binding to dsDNA.
The bright fluorescence signal and low background make TODi-1 ideal for staining nucleic acids on microarrays, as well as for nuclear and chromosome counterstaining in multicolor fluorescence labeling experiments. TODi-1 is non-cytotoxic and may be used for long-term monitoring of cell viability and dead cell detection in culture.
Chemical Properties
ex/em: 514/533 nm
Extinction coefficient (ε): 117000 cm??1M??1
Quantum yield (Φ): 0.34
Definition
ChEBI: ToTo-1 is an organic iodide salt and a cyanine dye. It has a role as a fluorochrome. It contains a ToTo-1(4+).
Abs/Em Maxima
514/532 nm
TOTO 1 Preparation Products And Raw materials
Raw materials
Preparation Products
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TOTO 1 Suppliers
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143413-84-7, TOTO 1Related Search:
TO-PRO-5
3-METHYL-2-((E)-3-[1-[3-(TRIMETHYLAMMONIO)PROPYL]-4(1H)-QUINOLINYLIDENE]-1-PROPENYL)-1,3-BENZOTHIAZOL-3-IUM DIIODIDE
3-METHYL-2-([1-[3-(TRIMETHYLAMMONIO)PROPYL]-4(1H)-QUINOLINYLIDENE]METHYL)-1,3-BENZOTHIAZOL-3-IUM DIIODIDE
TOTO 3