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olivetolic acid

Product Name
olivetolic acid
CAS No.
491-72-5
Chemical Name
olivetolic acid
Synonyms
Olivetolcarboxylic acid;2,4-Dihydroxy-6-pentylbenzoic acid;139400;olivetolic acid;olivanic acid powder 98%;Olivetolic acid in Methanol;Benzoic acid, 2,4-dihydroxy-6-pentyl-;Olivetolic acid 1000 μg/mL in Methanol
CBNumber
CB81340565
Molecular Formula
C12H16O4
Formula Weight
224.25
MOL File
491-72-5.mol
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olivetolic acid Property

Melting point:
143 °C
Boiling point:
403.9±25.0 °C(Predicted)
Density 
1.237±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
3.41±0.34(Predicted)
form 
Solid
color 
Light Beige to Light Brown
Stability:
Hygroscopic
InChI
InChI=1S/C12H16O4/c1-2-3-4-5-8-6-9(13)7-10(14)11(8)12(15)16/h6-7,13-14H,2-5H2,1H3,(H,15,16)
InChIKey
SXFKFRRXJUJGSS-UHFFFAOYSA-N
SMILES
C(O)(=O)C1=C(CCCCC)C=C(O)C=C1O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
26282
Product name
Olivetolic Acid
Packaging
25mg
Price
$93
Updated
2024/03/01
Cayman Chemical
Product number
26282
Product name
Olivetolic Acid
Packaging
5mg
Price
$31
Updated
2023/06/20
TRC
Product number
O533005
Product name
OlivetolicAcid
Packaging
100mg
Price
$180
Updated
2021/12/16
TRC
Product number
O533005
Product name
OlivetolicAcid
Packaging
500mg
Price
$490
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PXT0005334
Product name
OLIVETOLIC ACID
Purity
95.00%
Packaging
5MG
Price
$501.01
Updated
2021/12/16
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olivetolic acid Chemical Properties,Usage,Production

Uses

Olivetolic Acid is a precursor in the synthesis of primin and tetrahydrocannabinol.

Definition

ChEBI: A member of the class of benzoic acids that is salicylic acid in which the hydrogens ortho- and para- to the carboxy group are replaced by a pentyl and a hydroxy group, respectively.

Biosynthesis

Olivetolic acid (OLA) biosynthesis involves the condensation of one hexanoyl-CoA with three malonyl-CoAs by a type III PKS (tetraketide synthase) OLA synthase (C. sativa OLS; CsOLS) and an OLA cyclase (CsOAC), both enzymes were derived from the Cannabis species (C. sativa). Studies have achieved trace amount of OLA production in both E. coli and S. cerevisia[1]. Ma et al. find that Pseudomonas sp LvaE encoding a short-chain acyl-CoA synthetase can efficiently convert hexanoic acid to hexanoyl-CoA. The co-expression of the acetyl-CoA carboxylase, the pyruvate dehydrogenase bypass, the NADPH-generating malic enzyme, as well as the activation of peroxisomal β-oxidation pathway and ATP export pathway are effective strategies to redirect carbon flux toward OLA synthesis.

References

[1] Ma, J, Y. Gu, and P. Xu . "Biosynthesis of cannabinoid precursor olivetolic acid by overcoming rate-limiting steps in genetically engineered Yarrowia lipolytica." Cold Spring Harbor Laboratory(2021).

olivetolic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from olivetolic acid manufacturers

Jinan Jianfeng Chemical Co., Ltd
Product
olivetolic acid 491-72-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
3000kg
Release date
2023-12-08
Shaanxi Dideu Medichem Co. Ltd
Product
olivetolic acid 491-72-5
Price
US $1.00-50.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20000KG
Release date
2024-07-17
Henan Aochuang Chemical Co.,Ltd.
Product
olivetolic acid 491-72-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27

491-72-5, olivetolic acidRelated Search:


  • olivetolic acid
  • 2,4-Dihydroxy-6-pentylbenzoic acid
  • Olivetolcarboxylic acid
  • 139400
  • olivanic acid powder 98%
  • Benzoic acid, 2,4-dihydroxy-6-pentyl-
  • Olivetolic acid 1000 μg/mL in Methanol
  • Olivetolic acid in Methanol
  • 491-72-5