ChemicalBook > CAS DataBase List > PD 136450
PD 136450
- Product Name
- PD 136450
- CAS No.
- 139067-52-0
- Chemical Name
- PD 136450
- Synonyms
- Cam1189;Cam 1189;Cam-1189;PD 136450;(E)-4-[[(1R)-2-[[(2R)-2-(2-adamantyloxycarbonylamino)-3-(1H-indol-3-yl)-2-methylpropanoyl]amino]-1-phenylethyl]amino]-4-oxobut-2-enoic acid;2-Butenoic acid, 4-[[(1R)-2-[[(2R)-3-(1H-indol-3-yl)-2-methyl-1-oxo-2-[[(tricyclo[3.3.1.13,7]dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]-4-oxo-
- CBNumber
- CB81345898
- Molecular Formula
- C35H40N4O6
- Formula Weight
- 612.72
- MOL File
- 139067-52-0.mol
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PD 136450 Property
- Boiling point:
- 950.4±65.0 °C(Predicted)
- Density
- 1.33±0.1 g/cm3(Predicted)
- pka
- 3.49±0.10(Predicted)
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PD 136450 Chemical Properties,Usage,Production
Description
Cholecystokinin type B receptor antagonist PD-136,450 is a partial secretory agonist in the stomach and a full agonist in the pancreas of the rat. Gastrin (cholecystokinin type B (CCK-B)) receptor antagonists may help to elucidate the physiological role of gastrin, have therapeutic potential as acid antisecretory drugs, and may be of use as adjuvant therapy for gastrin sensitive tumours. The agonist effect of PD-136,450 is mediated via interaction with the gastrin (CCK-B) receptor in the stomach and the CCK-A receptor in the pancreas.
PD 136450 Preparation Products And Raw materials
Raw materials
Preparation Products
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PD 136450 Suppliers
- Tel
- +1-781-999-5354 +1-00000000000
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19892
- Advantage
- 58
- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 19696
- Advantage
- 58