ChemicalBook > CAS DataBase List > NQ301

NQ301

Product Name
NQ301
CAS No.
130089-98-4
Chemical Name
NQ301
Synonyms
NQ301;NQ 301; NQ-301;NQ301 >=98% (HPLC);NQ301 - Compound 211;inhibit,Inhibitor,NQ-301,NQ301,NQ 301,Thrombin;2-(4-Acetylanilino)-3-chloronaphthalene-1,4-dione;2-((4-acetylphenyl)amino)-3-chloronaphthalene-1,4-dione;2-[(4-Acetylphenyl)amino]-3-chloro-1,4-naphthalenedione;1,4-Naphthalenedione, 2-[(4-acetylphenyl)amino]-3-chloro-
CBNumber
CB81352274
Molecular Formula
C18H12ClNO3
Formula Weight
325.75
MOL File
130089-98-4.mol
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NQ301 Property

Melting point:
241-243 °C(Solv: ethanol (64-17-5))
Boiling point:
476.8±45.0 °C(Predicted)
Density 
1.40±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO:10.0(Max Conc. mg/mL);30.7(Max Conc. mM)
form 
powder
pka
-5.25±0.20(Predicted)
color 
faint red to dark red
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Safety

RIDADR 
UN 3077 9 / PGIII
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1337
Product name
NQ301
Purity
≥98% (HPLC)
Packaging
5mg
Price
$118
Updated
2024/03/01
Sigma-Aldrich
Product number
SML1337
Product name
NQ301
Purity
≥98% (HPLC)
Packaging
25mg
Price
$370
Updated
2024/03/01
Cayman Chemical
Product number
21958
Product name
NQ301
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
21958
Product name
NQ301
Packaging
5mg
Price
$100
Updated
2024/03/01
Cayman Chemical
Product number
21958
Product name
NQ301
Packaging
10mg
Price
$139
Updated
2024/03/01
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NQ301 Chemical Properties,Usage,Production

Uses

NQ 301 possess antiplatelet effect, making it an antithrombotic agent. It significantly inhibited the collagen-?, thrombin-?, arachidonic acid-?, thapsigargin- and calcium ionophore A23187-?induced aggregation of washed human platelets.

Biochem/physiol Actions

NQ301 is an antithrombotic agent. Recent study shows that NQ301 (Compound 211) is a highly potent, selective, non-competitive allosteric inhibitor of CD45 that selectively inhibits dephosphorylation of substrate Lck pY-505 versus Lck pY-393. NQ301 prevents T cell receptor-mediated activation of Lck, Zap-70 and MAPK, and IL-2 production in primary T-cells. NQ301 exhibits immunosuppressive activity in mice.

NQ301 Preparation Products And Raw materials

Raw materials

Preparation Products

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NQ301 Suppliers

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130089-98-4, NQ301Related Search:


  • NQ301
  • NQ301 - Compound 211
  • NQ 301; NQ-301
  • 2-((4-acetylphenyl)amino)-3-chloronaphthalene-1,4-dione
  • 2-(4-Acetylanilino)-3-chloronaphthalene-1,4-dione
  • 2-[(4-Acetylphenyl)amino]-3-chloro-1,4-naphthalenedione
  • 1,4-Naphthalenedione, 2-[(4-acetylphenyl)amino]-3-chloro-
  • NQ301 >=98% (HPLC)
  • inhibit,Inhibitor,NQ-301,NQ301,NQ 301,Thrombin
  • 130089-98-4