ChemicalBook > CAS DataBase List > butyryl timolol
butyryl timolol
- Product Name
- butyryl timolol
- CAS No.
- 106351-79-5
- Chemical Name
- butyryl timolol
- Synonyms
- butyryl timolol;O-Butyryltimolol;BUTYRYLTIMOLOL; BUTYRYL TIMOLOL; BUTYRYL-TIMOLOL;Butanoic acid, 1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]ethyl ester, (S)- (9CI)
- CBNumber
- CB81373404
- Molecular Formula
- C17H30N4O4S
- Formula Weight
- 386.51
- MOL File
- 106351-79-5.mol
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butyryl timolol Property
- Boiling point:
- 511.5±50.0 °C(Predicted)
- Density
- 1.169±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 8.74±0.10(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
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N-Bromosuccinimide Price
DC Chemicals
- Product number
- DC10693
- Product name
- O-Butyryltimolol
- Purity
- >98%
- Packaging
- 100mg
- Price
- $750
- Updated
- 2021/12/16
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butyryl timolol Chemical Properties,Usage,Production
Uses
Butyryltimolol, an effective precursor of Timolol, improves the corneal penetration of Timolol[1]. Butyryltimolol is a β-adrenergic blocker[2].
IC 50
β adrenergic receptor
References
[1] Chang SC, et al. Relative effectiveness of prodrug and viscous solution approaches in maximizing the ratio of ocular to systemic absorption of topically applied timolol. Exp Eye Res. 1988 Jan;46(1):59-69. DOI:10.1016/s0014-4835(88)80093-9
[2] Potter DE, et al. Ocular and cardiac beta-antagonism by timolol prodrugs, timolol and levobunolol. Curr Eye Res. 1988 Aug;7(8):755-9. DOI:10.3109/02713688809033206
butyryl timolol Preparation Products And Raw materials
Raw materials
Preparation Products
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