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norswertianolin

Product Name
norswertianolin
CAS No.
54954-12-0
Chemical Name
norswertianolin
Synonyms
norswertianolin;9H-Xanthen-9-one, 8-(β-D-glucopyranosyloxy)-1,3,5-trihydroxy-;1,3,5-Trihydroxy-8-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-9H-xanthen-9-one
CBNumber
CB81375059
Molecular Formula
C19H18O11
Formula Weight
422.34
MOL File
54954-12-0.mol
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norswertianolin Property

Melting point:
265 °C (decomp)
Boiling point:
833.7±65.0 °C(Predicted)
Density 
1.789±0.06 g/cm3(Predicted)
pka
6.73±0.20(Predicted)
form 
Solid
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PXT0002330
Product name
NORSWERTIANOLIN
Purity
95.00%
Packaging
5MG
Price
$504.47
Updated
2021/12/16
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norswertianolin Chemical Properties,Usage,Production

Uses

Norswertianolin acts as a CSE activator and is isolated from G. acuta. Norswertianolin may be a potential agent for cardiovascular diseases[1][2].

Definition

ChEBI: A beta-D-glucoside that is bellidin in which a beta-D-glucopyranosyl residue is attached at position O-8. A natural product found particularly in Gentiana campestris and <ital Gentiana germanica.

in vivo

Norswertianolin (4.4 mg/kg/day; s.c.; 1 week) improves CSE/H2S production[2].
Norswertianolin treatment attenuates the renal tubular injury in acute I/R. Norswertianolin also reduces I/R-stimulated ROS by DHE fluorescence intensity. Norswertianolin has anti-hypertension effects, inhibits vascular remodeling and reduces inflammation effects[2].

Animal Model:Male Sprague Dawley rats (10~12 weeks)[2]
Dosage:4.4 mg/kg/day
Administration:S.c.
Result:Improved CSE/H2S production.

References

[1] Ren K, et al. Effects of Four Compounds from Gentianella acuta (Michx.) Hulten on Hydrogen Peroxide-Induced Injury in H9c2 Cells. Biomed Res Int. 2019;2019:2692970. Published 2019 Jan 20. DOI:10.1155/2019/2692970
[2] Niu Y, et al. Norswertianolin Promotes Cystathionine γ-Lyase Activity and Attenuates Renal Ischemia/Reperfusion Injury and Hypertension. Front Pharmacol. 2021;12:677212. Published 2021 Jul 14. doi:10.3389/fphar.2021.677212

norswertianolin Preparation Products And Raw materials

Raw materials

Preparation Products

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norswertianolin Suppliers

China 33 Global 33
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
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China
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2376
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60
Wuhan ChemFaces Biochemical Co., Ltd.
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18607101326 15172504745
Fax
+86-27-84254680
Email
aileen@chemfaces.com
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China
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6905
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Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
89689
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60
Shanghai Uteam Biotechnology Co., Ltd.
Tel
021-36031160 13311776681
Email
3338195766@QQ.com
Country
China
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5093
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Shanghai Biological Technology Development Co., Ltd.
Tel
021-69955236-807 13918189704
Fax
021-65211385
Email
chinaruji@chinaruji.com
Country
China
ProdList
5095
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Chengdu Push Bio-Technology Co., Ltd.
Tel
028-85370565-229 18080489829
Email
18080489829@163.com
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China
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Shanghai Standard Technology Co.,Ltd.
Tel
021-021-57127007-6622-6622 17621252073
Fax
+86 (21) 5132-0077
Email
luzh@nature-standard.com
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China
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Nanjing Digger Medical Technology Co. Ltd.
Tel
025-025-51191215 18013836722
Fax
025-51191215
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2399235533@qq.com
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China
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Chengdu Peter-like Biotechnology Co., Ltd.
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18108052721 18108052721;
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2850505130@qq.com
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Chengdu Alfa Biotechnology Co.,Ltd.
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028-028-85142057 19983342022
Fax
028-85142057
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3591697873@qq.com
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54954-12-0, norswertianolinRelated Search:

HELICIN DESMETHYLBELLIDIFOLIN 1-METHOXYXANTHEN-9-ONE SWERTIANOLIN norswertianolin

  • norswertianolin
  • 9H-Xanthen-9-one, 8-(β-D-glucopyranosyloxy)-1,3,5-trihydroxy-
  • 1,3,5-Trihydroxy-8-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-9H-xanthen-9-one
  • 54954-12-0