1-arabinofuranosylcytosine-5'-stearylphosphate

Product Name: 1-arabinofuranosylcytosine-5'-stearylphosphate
CAS No.: 73532-83-9
Chemical Name: 1-arabinofuranosylcytosine-5'-stearylphosphate
Synonyms: YNK-01;Fosteabine;Stearyl-ara-CMP;Fosteabine (Cytarabine ocfosfate;Fosteabine (Synonyms: Cytarabine ocfosfate;1-arabinofuranosylcytosine-5'-stearylphosphate;2(1H)-Pyrimidinone, 4-amino-1-[5-O-[hydroxy(octadecyloxy)phosphinyl]-β-D-arabinofuranosyl]-;4-Amino-1-[5-O-[(hydroxy)(octadecyloxy)phosphinyl]-β-D-arabinofuranosyl]-1,2-dihydropyrimidin-2-one;(2R,3S,4S,5R)-5-[4-Amino-2-oxopyrimidin-1(2H)-yl]-3,4-dihydroxy-2-tetrahydrofuryl]methyl Octadecyl Hydrogen Phosphate
CBNumber: CB81381711
Molecular Formula: C27H50N3O8P
Formula Weight: 575.68
MOL File: 73532-83-9.mol

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1-arabinofuranosylcytosine-5'-stearylphosphate Property

Boiling point:: 711.6±70.0 °C(Predicted)
Density: 1.28±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 1.44±0.50(Predicted)

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Hazard and Precautionary Statements (GHS)

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1-arabinofuranosylcytosine-5'-stearylphosphate Chemical Properties,Usage,Production

Uses

Fosteabine is an oral and proagent analogue of cytarabine which is resistant to deoxycytidine deaminase.

Definition

ChEBI: Cytarabine ocfosfate is a pyrimidine ribonucleoside monophosphate.

References

[1] Maloisel F, et al. Results of a phase II trial of a combination of oral cytarabine ocfosfate (YNK01) and interferon alpha-2b for the treatment of chronic myelogenous leukemia patients in chronic phase. Leukemia. 2002 Apr;16(4):573-80. DOI:10.1038/sj.leu.2402433

1-arabinofuranosylcytosine-5'-stearylphosphate Preparation Products And Raw materials

Raw materials

Preparation Products

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1-arabinofuranosylcytosine-5'-stearylphosphate Suppliers

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73532-83-9, 1-arabinofuranosylcytosine-5'-stearylphosphateRelated Search:

ARA-CMP

1-arabinofuranosylcytosine-5'-stearylphosphate

4-Amino-1-[5-O-[(hydroxy)(octadecyloxy)phosphinyl]-β-D-arabinofuranosyl]-1,2-dihydropyrimidin-2-one

Stearyl-ara-CMP

YNK-01

Fosteabine (Synonyms: Cytarabine ocfosfate

Fosteabine (Cytarabine ocfosfate

Fosteabine

2(1H)-Pyrimidinone, 4-amino-1-[5-O-[hydroxy(octadecyloxy)phosphinyl]-β-D-arabinofuranosyl]-

(2R,3S,4S,5R)-5-[4-Amino-2-oxopyrimidin-1(2H)-yl]-3,4-dihydroxy-2-tetrahydrofuryl]methyl Octadecyl Hydrogen Phosphate

73532-83-9