ChemicalBook > CAS DataBase List > GR 64349

GR 64349

Product Name
GR 64349
CAS No.
137593-52-3
Chemical Name
GR 64349
Synonyms
GR 64349;GR-64349 (GR64349);LYS-ASP-SER-PHE-VAL-GLY-R-GAMMA-LACTAM-LEU-MET-NH2;[LYS3, GLY8-R-GAMMA-LACTAM-LEU9]NEUROKININ A (3-10);L-lysyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-valyl-(αS,3R)-3-amino-α-(2-methylpropyl)-2-oxo-1-pyrrolidineacetyl-L-methioninamide;L-Methioninamide,L-lysyl-L-a-aspartyl-L-seryl-L-phenylalanyl-L-valyl-(aS,3R)-3-amino-a-(2-methylpropyl)-2-oxo-1-pyrrolidineacetyl-;L-Methioninamide, L-lysyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-valyl-(αS,3R)-3-amino-α-(2-methylpropyl)-2-oxo-1-pyrrolidineacetyl-;L-Lys-L-Asp-L-Ser-L-Phe-L-Val-N-[(3R)-1-[(R)-1-[[[(S)-1-(Aminocarbonyl)-3-(methylthio)propyl]amino]carbonyl]-3-methylbutyl]-2-oxo-3α-pyrrolidinyl]-NH2
CBNumber
CB8138196
Molecular Formula
C42H68N10O11S
Formula Weight
921.11
MOL File
137593-52-3.mol
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GR 64349 Property

Boiling point:
1342.8±65.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble to 1 mg/ml in 20% ethanol / water
form 
Powder
pka
4.13±0.10(Predicted)
color 
White to off-white
Water Solubility 
Soluble to 1 mg/ml in water
Sequence
Lys-Asp-Ser-Phe-Val-{Aaa}-Leu-Met-NH2
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G113
Product name
GR 64349
Purity
>96%
Packaging
1mg
Price
$879
Updated
2025/07/31
Tocris
Product number
1668
Product name
GR 64349
Packaging
1
Price
$392
Updated
2021/12/16
TRC
Product number
G779515
Product name
GR 64349
Packaging
2.5mg
Price
$1360
Updated
2021/12/16
ApexBio Technology
Product number
B5159
Product name
GR 64349
Packaging
1mg
Price
$574
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008778
Product name
LYS-ASP-SER-PHE-VAL-GLY-R-GAMMA-LACTAM-LEU-MET-NH2
Purity
95.00%
Packaging
0.5MG
Price
$629.48
Updated
2021/12/16
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GR 64349 Chemical Properties,Usage,Production

Uses

GR 64349 acts as a potent and selective agonist at the NK-2 tachykinin receptor. Initiates changes in the colon, intestine and spinal cord.

Biological Activity

GR 64349 peptide acts as an agonist of neurokinin (NK2) receptor, which leads to reduced NK2 response to kainate and AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), but not to NMDA (N-methyl-D-aspartate).

storage

Store at -20°C

GR 64349 Preparation Products And Raw materials

Raw materials

Preparation Products

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GR 64349 Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
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137593-52-3, GR 64349Related Search:


  • L-Lys-L-Asp-L-Ser-L-Phe-L-Val-N-[(3R)-1-[(R)-1-[[[(S)-1-(Aminocarbonyl)-3-(methylthio)propyl]amino]carbonyl]-3-methylbutyl]-2-oxo-3α-pyrrolidinyl]-NH2
  • L-Methioninamide,L-lysyl-L-a-aspartyl-L-seryl-L-phenylalanyl-L-valyl-(aS,3R)-3-amino-a-(2-methylpropyl)-2-oxo-1-pyrrolidineacetyl-
  • LYS-ASP-SER-PHE-VAL-GLY-R-GAMMA-LACTAM-LEU-MET-NH2
  • [LYS3, GLY8-R-GAMMA-LACTAM-LEU9]NEUROKININ A (3-10)
  • GR 64349
  • L-lysyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-valyl-(αS,3R)-3-amino-α-(2-methylpropyl)-2-oxo-1-pyrrolidineacetyl-L-methioninamide
  • GR-64349 (GR64349)
  • L-Methioninamide, L-lysyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-valyl-(αS,3R)-3-amino-α-(2-methylpropyl)-2-oxo-1-pyrrolidineacetyl-
  • 137593-52-3
  • C42H68N10O11S
  • Agonist
  • BioChemical
  • Amino Acids and Peptides
  • Biochemicals and Reagents
  • Peptides
  • Tachykinins
  • AgonistPeptides for Cell Biology
  • Neuropeptides
  • Peptides for Cell Biology
  • Tachykinins