ChemicalBook > CAS DataBase List > WIN 62005
WIN 62005
- Product Name
- WIN 62005
- CAS No.
- 152633-54-0
- Chemical Name
- WIN 62005
- Synonyms
- WIN 62005;Win62005,Win 62005;2H-Imidazo[4,5-b]pyridin-2-one, 1,3-dihydro-5-methyl-6-(4-pyridinyl)-
- CBNumber
- CB81382864
- Molecular Formula
- C12H10N4O
- Formula Weight
- 226.23
- MOL File
- 152633-54-0.mol
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WIN 62005 Property
- Density
- 1.45±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 7.36±0.60(Predicted)
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WIN 62005 Chemical Properties,Usage,Production
Uses
Win-62005 is a cyclic AMP phosphodiesterase III (PDE III) inhibitor with Kis of 25 and 26 nM for rat heart and canine aorta, respectively.
in vivo
After p.o. administration of 1 mg/kg Win-62005, LVdP/dtmax is significantly increased in 30 min and remains increased for at least 6 h[1].
References
[1] Dundore RL, et al. Species-dependent pharmacodynamic effects of the selective low Km cyclic AMP phosphodiesterase III inhibitors WIN 58993 and WIN 62005. J Cardiovasc Pharmacol. 1995 Jan;25(1):14-21. DOI:10.1097/00005344-199501000-00004
WIN 62005 Preparation Products And Raw materials
Raw materials
Preparation Products
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WIN 62005 Suppliers
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- 021-58955995
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- United States
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- +1-781-999-5354; +17819995354
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- China
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- China
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- Tel
- +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
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- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
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- 58