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Naphthalene, 1,8-dimethoxy-

Product Name
Naphthalene, 1,8-dimethoxy-
CAS No.
10075-66-8
Chemical Name
Naphthalene, 1,8-dimethoxy-
Synonyms
1,8-dimethoxynaphthalene;Naphthalene, 1,8-dimethoxy-
CBNumber
CB81465646
Molecular Formula
C12H12O2
Formula Weight
188.22
MOL File
10075-66-8.mol
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Naphthalene, 1,8-dimethoxy- Property

Melting point:
160-161℃ (ethanol )
storage temp. 
2-8°C
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0092319
Product name
NAPHTHALENE, 1,8-DIMETHOXY-
Purity
95.00%
Packaging
5MG
Price
$497.92
Updated
2021/12/16
Activate Scientific
Product number
AS80674
Product name
1,8-Dimethoxynaphthalene
Purity
95+%
Packaging
1g
Price
$1482
Updated
2021/12/16
AK Scientific
Product number
1153CM
Product name
1,8-Dimethoxynaphthalene
Packaging
1g
Price
$1545
Updated
2021/12/16
Alichem
Product number
10075668
Product name
1,8-Dimethoxynaphthalene
Packaging
1g
Price
$1769.25
Updated
2021/12/16
Crysdot
Product number
CD41002381
Product name
1,8-Dimethoxynaphthalene
Purity
95+%
Packaging
100mg
Price
$272
Updated
2021/12/16
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Naphthalene, 1,8-dimethoxy- Chemical Properties,Usage,Production

Chemical Properties

off-white powder

Synthesis

569-42-6

77-78-1

10075-66-8

The synthetic procedure was optimized based on literature reports. 1,8-Dihydroxynaphthalene (200 mg, 1.25 mmol) was dissolved in 10 mL of acetone and potassium carbonate (1.73 g, 12.5 mmol) and dimethyl sulfate (1.19 mL, 12.5 mmol) were added sequentially. The resulting inhomogeneous mixture was heated to 70 °C and stirred at this temperature for 24 hours. After completion of the reaction, the mixture was cooled to room temperature and the reaction was quenched with deionized water (15 mL). The aqueous phase was extracted with dichloromethane (3 x 10 mL). The organic phases were combined, dried with anhydrous sodium sulfate and filtered. The filtrate was concentrated under reduced pressure to give pure 1,8-dimethoxynaphthalene (216 mg, 92% yield) as a light yellow solid. All spectral data were in agreement with literature reports. Thin layer chromatography (TLC) Rf = 0.46 (ethyl acetate:hexane = 1:9); 1H NMR (400 MHz, CDCl3) δ 7.41 (2H, dd, J = 8.2, 1.4 Hz), 7.39-7.35 (2H, m), 6.86 (2H, dd, J = 7.4, 1.2 Hz), 3.99 (6H, s); 13C NMR (100 MHz, CDCl3) δ 157.2, 137.5, 126.5, 121.0, 117.8, 106.3, 56.6; Fourier Transform Infrared Spectroscopy (FTIR, ATR, solid) 3001, 2956, 2836, 1580, 1460, 1427, 1386, 1348, 1273, 1237 cm-1; High Resolution Mass Spectrometry (HRMS, APCI+) calculated value C12H13O2 [M + H]+: 189.0911, measured value: 189.0917.

References

[1] Turkish Journal of Chemistry, 2018, vol. 42, # 5, p. 1398 - 1407
[2] Journal of the Chemical Society, 1956, p. 2412,2415
[3] Helvetica Chimica Acta, 1950, vol. 33, p. 595,596
[4] Journal of Organic Chemistry, 1980, vol. 45, # 6, p. 1149 - 1151

Naphthalene, 1,8-dimethoxy- Preparation Products And Raw materials

Raw materials

Preparation Products

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Naphthalene, 1,8-dimethoxy- Suppliers

Shanghai Ennopharm Co., Ltd.
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Jinan Kaixi Biotechnology Co., Ltd.
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Beijing Hechemist Technology CO.,LTD
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Amadis Chemical Company Limited
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View Lastest Price from Naphthalene, 1,8-dimethoxy- manufacturers

Career Henan Chemical Co
Product
Naphthalene, 1,8-dimethoxy 10075-66-8
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2020-01-12