ChemicalBook > CAS DataBase List > 1-Naphthalenamine, 4-cyclopropyl-
1-Naphthalenamine, 4-cyclopropyl-
Uses- Product Name
- 1-Naphthalenamine, 4-cyclopropyl-
- CAS No.
- 878671-94-4
- Chemical Name
- 1-Naphthalenamine, 4-cyclopropyl-
- Synonyms
- 1-phthalemine, 4-cyclopropyl-;4-cyclopropyl-1-naphthalamine;4- cyclopropyl-1-naphthylamine;4-Cyclopropylnaphthalen-1-aMine;4-Cyclopropyl-1-Naphthalenamine;1-amino-4-cyclopropylnaphthalene;1-Naphthalenamine, 4-cyclopropyl-;4- cyclopropyl-1-naphthylamine oxalate;4-Cyclopropyl-1-naphthalenaMine oxalate
- CBNumber
- CB81465732
- Molecular Formula
- C13H13N
- Formula Weight
- 183.25
- MOL File
- 878671-94-4.mol
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1-Naphthalenamine, 4-cyclopropyl- Property
- Boiling point:
- 361.6±21.0 °C(Predicted)
- Density
- 1.191
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 4.62±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
TRC
- Product number
- C997838
- Product name
- 4-Cyclopropylnaphthalen-1-amine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
TRC
- Product number
- C997838
- Product name
- 4-Cyclopropylnaphthalen-1-amine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
AK Scientific
- Product number
- 3518DL
- Product name
- 4-Cyclopropylnaphthalen-1-amine
- Packaging
- 250mg
- Price
- $70
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- CHM0094245
- Product name
- 1-NAPHTHALENAMINE, 4-CYCLOPROPYL-
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $501.03
- Updated
- 2021/12/16
Ambeed
- Product number
- A175437
- Product name
- 4-Cyclopropylnaphthalen-1-amine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
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1-Naphthalenamine, 4-cyclopropyl- Chemical Properties,Usage,Production
Uses
4-Cyclopropyl-1-naphthylamine is an amine derivative that can be used as an intermediate in organic synthesis.
Synthesis
2298-07-9
411235-57-9
878671-94-4
Tetrakis(triphenylphosphine)palladium (0.26 g, 0.23 mmol) and potassium phosphate (1.67 g, 7.87 mmol) were added to a 50 mL round-bottomed flask under nitrogen protection using 4-bromo-1-naphthylamine (0.50 g, 2.25 mmol) and cyclopropylboronic acid (0.212 g, 2.47 mmol). A solvent mixture of dioxane and water (25:1, 26 mL) was then added, and after three nitrogen displacements, the reaction mixture was heated to reflux in a 90 °C oil bath for 6 hours. After completion of the reaction, it was cooled to room temperature and filtered to remove insoluble material. The filtrate was concentrated under reduced pressure to remove the solvent, diluted with 50 mL of water and extracted with ethyl acetate (2 x 10 mL). The organic layers were combined, washed twice with saturated brine, dried over anhydrous sodium sulfate, filtered and concentrated to give the intermediate 4-cyclopropyl-1-aminonaphthalene as a purplish red oil in 95.3% yield.
References
[1] Chemical Biology and Drug Design, 2016, vol. 88, # 2, p. 241 - 253
[2] Patent: CN105175414, 2017, B. Location in patent: Paragraph 0040
[3] Patent: CN105566237, 2016, A. Location in patent: Paragraph 0060; 0061; 0062
[4] Patent: CN106083847, 2016, A. Location in patent: Paragraph 0133; 0134; 0170; 0171
[5] Patent: WO2006/26356, 2006, A2. Location in patent: Page/Page column 35-36
1-Naphthalenamine, 4-cyclopropyl- Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-Naphthalenamine, 4-cyclopropyl- manufacturers
Guangzhou Sunton Biotechnology Co., Ltd.
- Product
- 4- cyclopropyl-1-naphthylamine 878671-94-4
- Price
- US $48.00-40.00/KG
- Min. Order
- 1公斤
- Purity
- 98%
- Supply Ability
- 50 tons
- Release date
- 2021-06-11
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 1-Naphthalenamine, 4-cyclopropyl- 878671-94-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 1-Naphthalenamine, 4-cyclopropyl- 878671-94-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
878671-94-4, 1-Naphthalenamine, 4-cyclopropyl-Related Search:
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3H-1,2,4-Triazole-3-thione, 5-amino-4-(4-cyclopropyl-1-naphthalenyl)-2,4-dihydro
1-Naphthalenamine, 4-cyclopropyl-