α- Erythroidine
- Product Name
- α- Erythroidine
- CAS No.
- 466-80-8
- Chemical Name
- α- Erythroidine
- Synonyms
- a-Erythroidine;1,2,6,7-Tetradehydro-12,17-dihydro-3β-methoxy-16(15H)-oxaerythrinan-15-one;1H,12H-Benzo[i]pyrano[3,4-g]indolizin-12-one, 2,6,8,9,9a,10-hexahydro-2-methoxy-, (2R,9aS,13bS)-
- CBNumber
- CB81470765
- Molecular Formula
- C16H19NO3
- Formula Weight
- 273.33
- MOL File
- 466-80-8.mol
α- Erythroidine Property
- Melting point:
- 58-60°
- alpha
- D27 +136° (c = 0.5 in water)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- S284459
- Product name
- 12-METHOXY-4,4A,5,6,12,13-HEXAHYDRO-8H-PYRANO(4'',3'':3,4)PYRIDO(2,1-I)INDOL-2-ONE
- Purity
- AldrichCPR
- Packaging
- 25MG
- Price
- $110
- Updated
- 2024/03/01
- Product number
- PXT0002177
- Product name
- ALPHA-ERYTHROIDINE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.88
- Updated
- 2021/12/16
- Product number
- CHM0300164
- Product name
- 12-METHOXY-4,4A,5,6,12,13-HEXAHYDRO-8H-PYRANO(4',3':3,4)PYRIDO(2,1-I)INDOL-2-ONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $505.82
- Updated
- 2021/12/16
α- Erythroidine Chemical Properties,Usage,Production
Purification Methods
Recrystallise -erythroidine from pentane. It is best prepared freshly from the more stable hydrochloride. The hydrochloride (1.3g) in H2O (20mL) is basified with NaHCO3 to pH ~8 and extracted with *C6H6 (6 x 10mL). The combined extracts are evaporated to a small volume and refrigerated. The free base separates as white hygroscopic crystals m 52-55o, which are recrystallised from pentane. Although stable in solution, the crystals turn brown on exposure to air. -Erythroidine hydrochloride is best purified by dissolving 10g in H2O (100mL), adjusting the pH to 8 with aqueous NaHCO3, extracting with *C6H6 (4 x 20mL), evaporating to 20mL, passing through activated Al2O3 and eluting with *C6H6. The eluate is evaporated to a small volume and the crystals are collected, dissolved in EtOH and dry HCl gas passed through to give the pure hydrochloride. When recrystallised from EtOH, it has m 226-228o(dec), and [ ] D 32 +118o (c 0.5, H2O). It has max 224nm ( 35,500); compare with -erythroidine hydrochloride below. [Boelkeleide & Grundon J Am Chem Soc 75 2563 1953, Boekeleide & Morrison J Am Chem Soc 80 3905 1958, abs config: Hill & Shearer J Org Chem 2 7 3342 1955, Beilstein 27 III/IV 3569.]