5,7,8,4''-TETRAMETHOXYFLAVONE

Product Name: 5,7,8,4''-TETRAMETHOXYFLAVONE
CAS No.: 6601-66-7
Chemical Name: 5,7,8,4''-TETRAMETHOXYFLAVONE
Synonyms: 8-Tetramethoxyflavone;tetramethylisoscutellarein;5,7,8,4'-Tetramethoxyflavone;4’,5,7,8-Tetramethoxyflavone;5,7,8-trimethoxy-2-(4-methoxyphenyl)chromen-4-one;5,7,8,4'- tetramethoxyflavone 6-Demethoxytangeretin;5,7,8-Trimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one;4H-1-Benzopyran-4-one, 5,7,8-trimethoxy-2-(4-methoxyphenyl)-;Cluster of differentiation 246,6Demethoxytangeretin,Anaplastic lymphoma kinase (ALK),Anaplastic lymphoma kinase,6-Demethoxytangeretin,CD246,inhibit,ALK tyrosine kinase receptor,6 Demethoxytangeretin,Inhibitor
CBNumber: CB81484236
Molecular Formula: C19H18O6
Formula Weight: 342.34
MOL File: 6601-66-7.mol

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5,7,8,4''-TETRAMETHOXYFLAVONE Property

Melting point:: 216-217℃ (methanol )
Boiling point:: 536.9±50.0 °C(Predicted)
Density: 1.243±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: FT65329
Product name: 5,7,8,4'-Tetramethoxyflavone
Packaging: 1mg
Price: $195
Updated: 2021/12/16

ChemScene

Product number: CS-0032143
Product name: 6-Demethoxytangeretin
Purity: 99.28%
Packaging: 5mg
Price: $202
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FT65329
Product name: 5,7,8,4'-Tetramethoxyflavone
Packaging: 2mg
Price: $300
Updated: 2021/12/16

ChemScene

Product number: CS-0032143
Product name: 6-Demethoxytangeretin
Purity: 99.28%
Packaging: 10mg
Price: $343
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FT65329
Product name: 5,7,8,4'-Tetramethoxyflavone
Packaging: 5mg
Price: $625
Updated: 2021/12/16

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5,7,8,4''-TETRAMETHOXYFLAVONE Chemical Properties,Usage,Production

Chemical Properties

Pale yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Citrus aurantium.

Uses

6-Demethoxytangeretin is a flavonoid compound that can be isolated from Citrus reticulata. 6-Demethoxytangeretin has anti-inflammatory and anti-allergic activities and can inhibit the production of IL-6 and the expression of related genes in human mast cells through the ALK and MAPK pathways. 6-Demethoxytangeretin can promote CRE-mediated transcription in hippocampal neurons[1][2].

References

[1] Kim YM, et al. A citrus flavonoid, 6-demethoxytangeretin, suppresses production and gene expression of interleukin-6 in human mast cell-1 via anaplastic lymphoma kinase and mitogen-activated protein kinase pathways. Biol Pharm Bull. 2014;37(5):871-6. Epub 2014 Feb 5. DOI:10.1248/bpb.b13-00875
[2] Kawahata I, et al. Potent activity of nobiletin-rich Citrus reticulata peel extract to facilitate cAMP/PKA/ERK/CREB signaling associated with learning and memory in cultured hippocampal neurons: identification of the substances responsible for the pharmacological action. J Neural Transm (Vienna). 2013 Oct;120(10):1397-409. DOI:10.1007/s00702-013-1025-x

5,7,8,4''-TETRAMETHOXYFLAVONE Preparation Products And Raw materials

Raw materials

Preparation Products

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5,7,8,4''-TETRAMETHOXYFLAVONE Suppliers

China 92 United Kingdom 2 United States 7 Global 101

BioBioPha Co., Ltd.

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Chengdu Biopurify Phytochemicals Ltd.

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Chengdu Herbpurify Co.Ltd.

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Wuhan ChemFaces Biochemical Co., Ltd.

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EMMX Biotechnology LLC

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Shanghai YuanYe Biotechnology Co., Ltd.

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Beijing Jin Ming Biotechnology Co., Ltd.

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View Lastest Price from 5,7,8,4''-TETRAMETHOXYFLAVONE manufacturers

Shanghai Standard Technology Co., Ltd.

Product: 6-Demethoxytangeretin 6601-66-7
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-05-22

Career Henan Chemical Co

Product: 5,7,8,4''-TETRAMETHOXYFLAVONE 6601-66-7
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-10

6601-66-7, 5,7,8,4''-TETRAMETHOXYFLAVONERelated Search:

7-HYDROXYFLAVONE Tetramethylammonium hydroxide FLAVONE cis-4-hydroxy-alpha,alpha,4-trimethylcyclohexanemethanol 5,7,3'-Trihydroxy-6,4',5'-triMethoxyflavone NARINGENIN CHALCONE NARIRUTIN Naringin Naringin dihydrochalcone Naringenin Quercetagetin 3,5,6,7,3',4'-hexamethyl ether PONCIRIN 3,3',4',5,6,7,8-heptamethoxyflavone Cobalt tetramethoxyphenylporphyrin Fisetin

8-Tetramethoxyflavone

5,7,8-trimethoxy-2-(4-methoxyphenyl)chromen-4-one

4H-1-Benzopyran-4-one, 5,7,8-trimethoxy-2-(4-methoxyphenyl)-

5,7,8,4'- tetramethoxyflavone 6-Demethoxytangeretin

tetramethylisoscutellarein

Cluster of differentiation 246,6Demethoxytangeretin,Anaplastic lymphoma kinase (ALK),Anaplastic lymphoma kinase,6-Demethoxytangeretin,CD246,inhibit,ALK tyrosine kinase receptor,6 Demethoxytangeretin,Inhibitor

5,7,8-Trimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

4’,5,7,8-Tetramethoxyflavone

5,7,8,4'-Tetramethoxyflavone

6601-66-7

Tetra-substituted Flavones